Gene editing
We offer a large selection of products for CRISPR/Cas9- and Cre recombinase-based gene editing.
CRISPR/Cas9 technology has revolutionized gene editing, allowing a previously unattainable level of genomic targeting, efficiency, and simplicity. Our Guide-it product line further improves the usability of the CRISPR/Cas9 system by providing a streamlined method for every step of the gene-editing process.
We offer a large selection of products for CRISPR/Cas9- and Cre recombinase-based gene editing.
CRISPR/Cas9 technology has revolutionized gene editing, allowing a previously unattainable level of genomic targeting, efficiency, and simplicity. Our Guide-it product line further improves the usability of the CRISPR/Cas9 system by providing a streamlined method for every step of the gene-editing process.
In addition, we provide viral and gesicle delivery systems for Cre recombinase-based genome editing experiments.
Guide-it Knockin Screening Kit
Rapid, sensitive detection of single-nucleotide substitutions or insertions for precise genome editing applications.
Gene editing resources
Product finder
Use this gene editing product finder to quickly locate kits for screening, delivery, and downstream assays.
CRISPR tools and information
What is CRISPR/Cas9? Need help designing the best guide RNAs? Learn all this and more.
Genome-wide library screening
Learn how to conduct a CRISPR/Cas9 guide RNA library phenotypic screen and view data demonstrating the use of our library.
CRISPR/Cas9 knockouts
Technotes and tools used to create or study CRISPR-Cas9-mediated gene knockouts (indels).
CRISPR/Cas9 knockins
Information, technotes and tools used to create or study gene knockouts by CRISPR/Cas9 and HDR.
A fast and reliable method for SNP screening in genome editing experiments
In this webinar, Montse Morell, Ph.D. (Takara Bio USA, Inc.) presents the Guide-it SNP Screening Kit, a solution she developed to enable rapid, accurate detection of single-nucleotide substitutions and confirmation of successful HDR in edited cells. She also demonstrates an application of the kit in the development of disease models using iPSCs.
Video protocol: editing human iPSCs with CRISPR/Cas9 and single-cell cloning
In this video protocol, we provide step-by-step instructions for generating edited human iPS cell lines using electroporation-based delivery of CRISPR/Cas9 RNP complexes and single-cell cloning. This high-efficiency workflow greatly improves single-cell survival post-seeding, thanks to the Cellartis DEF-CS culture system.
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