Study immune repertoires to develop vaccines for HIV
Developing a vaccine for the human immunodeficiency virus (HIV) requires a deep understanding of our immune system. The immune system is made up of various cell types, such as B lymphocytes (B cells) and T lymphocytes (T cells) which execute their effector functions via binding to specific antigens recognized by B-cell receptors (BCRs) and T-cell receptors (TCRs), respectively. Demystifying BCR and TCR sequences is crucial to fully understand adaptive immune responses so we can develop optimal vaccine candidates and vaccination strategies.
With decades of expertise in NGS assays, our immune profiling products are known for their unmatched sensitivity and superior accuracy. Take a deeper dive into our immune profiling solutions so you can conduct safe and effective screening of vaccine candidates
Our immune profiling solutions
SMART-Seq Human BCR (with UMIs) captures the most heavily mutated BCR sequences for all isotypes to facilitate HIV vaccine research and antiretroviral therapy.
SMART-Seq Human TCR (with UMIs) is the first commercial solution for profiling TCR sequences from rhesus macaques, facilitating HIV vaccine research.
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