License and patent statements

ID #	Description
8	For Research Use Only, Not for Use in Humans.
9	These products are sold under license from the Fred Hutchinson Cancer Research Center. Rights to use this product are limited to research only. No other rights are conveyed. Inquiry into the availability of a license to broader rights or the use of this product for commercial purposes should be directed to Fred Hutchinson Cancer Research Center, Technology Transfer Office, 1100 Fairview Avenue North, C2M-027, Seattle, WA 98109. Purchase of this product does not grant rights to: (1) offer the materials or any derivatives thereof for resale; or (2) to distribute or transfer the materials or any derivatives thereof to third parties.
13	Use of the MSCV Retroviral Expression System is exclusively licensed from Robert G. Hawley, Ph.D. Academic research institutions are granted an automatic license with the purchase of this product to use the MSCV Retroviral Expression System only for internal, academic research purposes. This limitation expressly excludes the right to sell or otherwise transfer the MSCV system or its component parts to third parties. All other users and purchasers are required to obtain a license from Takara Bio USA, Inc. prior to purchasing these reagents or using them for any purpose. For information on licensing please contact a licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com.
24	The RCFPs (including DsRedExpress, DsRedExpress2, and E2-Crimson) are covered by one or more of the following U.S. Patent Nos. 7,166,444; 7,157,565; 7,217,789; 7,150,979; 8,093,450 and 8,461,769.
25	This product is covered by U.S. Patent No. 6,303,362.
28	This product is covered by the claims of U.S. Patent No. 7,575,860 and its foreign counterpart patent claims.
39	AcGFP is covered by U.S. Patent No. 7,432,053.
42	Use of the Tetracycline controllable expression systems (the "Tet Technology") is covered by a series of patents including U.S. Patent # 7541446, # 8383364, # 9181556 , European patents EP # 1200607, # 1954811, #2352833 and corresponding patent claims outside these regions which are proprietary to TET Systems GmbH & Co. KG. Academic research institutions are granted an automatic license with the purchase of this product to use the Tet Technology only for internal, academic research purposes, which license specifically excludes the right to sell, or otherwise transfer, the Tet Technology or its component parts to third parties. Notwithstanding the above, academic and not-for profit research institutions whose research using the Tet Technology is sponsored by for profit organizations, which shall receive ownership to any data and results stemming from the sponsored research, shall need a commercial license agreement from TET Systems in order to use the Tet Technology. In accepting this license, all users acknowledge that the Tet Technology is experimental in nature. TET Systems GmbH & Co. KG makes no warranties, express or implied or of any kind, and hereby disclaims any warranties, representations, or guarantees of any kind as to the Tet Technology, patents, or products. All others are invited to request a license from TET Systems GmbH & Co. KG prior to purchasing these reagents or using them for any purpose. Takara Bio USA, Inc. is required by its licensing agreement to submit a report of all purchasers of the Tet-controllable expression system to TET Systems. For license information, please contact: GSF/CEO TET Systems GmbH & Co. KG, Im Neuenheimer Feld 582 69120 Heidelberg Germany Tel: +49 6221 5880400 Fax: +49 6221 5880404 email: info@tetsystems.com or use the electronic licensing request form via http://www.tetsystems.com/ip-licensing/licensing/for-profit-research
44	The DsRed-Monomer and the Fruit Fluorescent Proteins are covered by one or more of the following U.S. Patents: 7,005,511; 7,157,566; 7,393,923 and 7,250,298.
45	S.V. Markova, S. Golz, L.A. Frank, B. Kalthof, and E.S. Vysotski (2004): Cloning and Expression of cDNA for a Luciferase from the marine copepod Metridia longa. J.Biol.Chem 279, 3212-3117. This product is covered by U.S. Patent No. 7,297,483.
47	Portions of this product are covered by several patent applications owned by, or licensed to, Dharmacon Inc (dba Horizon Discovery). The purchase of this product conveys to the buyer the limited, non-exclusive, non-transferable right (without the right to resell, repackage, or further sublicense) under these patent rights to perform the viral infection methods using the lentiviral vectors claimed in those patent applications for research purposes solely in conjunction with this product. No other license is granted to the buyer whether expressly, by implication, by estoppel or otherwise. In particular, the purchase of this product does not include nor carry any right or license to use, develop, or otherwise exploit this product commercially, and no other rights are conveyed to the buyer to use the product or components of the product for any other purposes, including without limitation, provision of services to a third party, generation of commercial databases, or clinical diagnostics or therapeutics. This product is sold pursuant to a license from Horizon Discovery, and Horizon Discovery, reserves all other rights under these patent rights. For information on purchasing a license to the patent rights for uses other than in conjunction with this product or to use this product for purposes other than research, please contact Horizon Discovery, legal-contracts@horizondiscovery.com.
55	cPPT Element. This product and its use are the subject to one or more of the following U.S. Pat. Nos. 8,093,042 and 10,407,695 and foreign equivalents. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot disclose information, sell or otherwise transfer this product, its components or materials made using this product or its components to a third party or otherwise use this product or its components or materials made using this product or its components for any commercial purposes. If the buyer is not willing to accept the limitations of this limited use statement, Takara Bio USA, Inc. is willing to accept return of the product with a full refund. For information on purchasing a license to the DNA-Flap technology for purposes other than research, contact the Transfer of Technology Office, Institut Pasteur, 28 rue du Docteur Roux, 75 724 Paris Cedex 15 (www.pasteur.fr).
57	This product is covered by U.S. Patent No. 8,173,792.
60	Use of the Antibody Array in combination with its associated buffers is covered under U.S. Patent No. 7,354,721.
63	Use of this product is covered by one or more of the following U.S. Patent Nos. and corresponding patent claims outside the U.S.: 6,998,115; 7,427,394. This product is intended for research purposes only. It may not be used for (i) any human or veterinary use, including without limitation therapeutic and prophylactic use, (ii) any clinical use, including without limitation diagnostic use, (iii) screening of chemical and/or biological compounds for the identification of pharmaceutically active agents (including but not limited to screening of small molecules), target validation, preclinical testing services, or drug development. Any use of this product for any of the above mentioned purposes requires a license from the Massachusetts Institute of Technology.
72	Living Colors Fluorescent Protein Products: Not-For-Profit Entities: Orders may be placed in the normal manner by contacting your local representative or Takara Bio USA, Inc. Customer Service. Any and all uses of this product will be subject to the terms and conditions of the Non-Commercial Use License Agreement (the “Non-Commercial License”), a copy of which can be found below. As a condition of sale of this product to you, and prior to using this product, you must agree to the terms and conditions of the Non-Commercial License. Under the Non-Commercial License, Takara Bio USA, Inc. grants Not-For-Profit Entities a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial scientific research use only. Such license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to third parties. No modifications to the product may be made without express written permission from Takara Bio USA, Inc. Any other use of this product requires a different license from Takara Bio USA, Inc. For license information, please contact a licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com. For-Profit Entities wishing to use this product are required to obtain a license from Takara Bio USA, Inc. For license information, please contact a licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com. Not-For-Profit Non-Commercial Use License:
82	The RetroPack PT67 Cell Line is covered under U.S. Patent No. 5,766,945, which has been assigned to the Fred Hutchinson Cancer Research Center. Rights to use this product are limited to research only. No other rights are conveyed. Inquiry into the availability of a license to broader rights or the use of this product for commercial purposes should be directed to Fred Hutchinson Cancer Research Center, Technology Transfer Office, 1100 Fairview Avenue North, C2M-027, Seattle, WA 98109. Purchase of this product does not grant rights to: 1. offer the materials or any derivatives thereof for resale; 2. to distribute or transfer the materials or any derivatives thereof to third parties.
83	The Living Colors mCherry Monoclonal Antibody has been obtained from National University of Shimane.
88	This product is sold under license from RIKEN and Tokyo Metropolitan Organization for Medical Research. This product is the subject of U.S. Patent No. 8,182,987 and its foreign counterparts.
89	This product is protected by U.S. Patent 9,945,850 and additional pending patent. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
91	This product is intended for in vitro research purposes only. It may not be used for (i) any human or veterinary use, including without limitation therapeutic and prophylactic use, (ii) any clinical use, including without limitation diagnostic and prognostic use, (iii) screening of chemical and/or biological compounds for the identification of pharmaceutically active agents (including but not limited to screening of small molecules), target validation, preclinical testing services, or drug development or (iv) any commercial purposes, including without limitation the performance of contract research or provision of services to a third party and the manufacture of products for general sale. Any use of this product for any of the abovementioned purposes requires a license from the Massachusetts Institute of Technology.
99	iDimerize and Shield1 Technologies: This product is sold under license from ARIAD Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, for use only in internal research conducted by the buyer, which license expressly excludes the right to sell or otherwise transfer the product to third parties and is expressly made subject to compliance with Takara Bio USA, Inc.’s general Terms and Conditions of Sale and any other restrictions set forth on the product’s web page. No right is given to use this product or its components for any other purpose including, but not limited to diagnostic, therapeutic and/or prophylactic applications for or in human beings, animals and/or plants, including but not limited to gene and cell therapy applications, whether in vitro, ex vivo or in vivo, in foods, drugs, devices or cosmetics of any kind, or for consumption by or use in connection with or administration or application to humans or veterinary treatment of animals, or to provide any services, including research services, to third parties. For information regarding licenses for uses other than internal research, please contact a licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com.
223	This product sold under license from AdVec, Inc.
225	Gesicle Technology. This product and its use are the subject of European patents and patent applications related to EP09306091, owned by Inserm Transfert. For research use only – not for therapeutic or diagnostic use in humans. No rights granted other that the right to use for research purposes. In addition, Inserm Transfert is the owner of European patent application EP09306092.9 relating to the use of microvesicles for cell engineering purposes. The products should not be used to develop, make, have made, use and sell or otherwise distribute any product, composition, method, service or process for commercial services that would infringe said patent application, unless a license is negotiated with Inserm Transfert, at 7 rue Watt, 75013 Paris, France (www.inserm-transfert.fr).
246	This product is protected by U.S. Patent 9,428,794, and additional pending US and foreign patents. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
259	Patent pending.
261	Vectalys’ technology Vectalys’ highly concentrated and purified lentiviral vectors and its use are covered by U.S. Patent No. 13/0029379 and WO 2013/014537. The purchase price of this product includes limited, nontransferable rights to use this product solely for internal research purposes. Academic and not-for-profit research institutions whose research using the Vectalys’ Technology or the product obtained by the Vectalys’ technology is sponsored by for profit organizations, which shall receive ownership to all data and results stemming from the sponsored research, shall need a commercial license agreement from Vectalys in order to use the Vectalys’ Technology or the product obtained by the Vectalys’ technology. Please contact Vectalys for information on purchasing a license to use these products for commercial purposes: Parc Technologique du Canal, Bâtiment Canal Biotech II, 3, rue des satellites, 31400 Toulouse (France), TEL: +33(0)5 61 28 70 75, EMAIL: sandy.darrigan@vectalys.com
262	Vectalys Technology Vectalys’ highly concentrated and purified lentiviral vectors and its use are covered by U.S. Patent No. 13/0029379 and WO 2013/014537. The purchase price of this product includes limited, nontransferable rights to use this product solely for internal research purposes. Academic and not-for-profit research institutions whose research using the Vectalys’ Technology or the product obtained by the Vectalys’ technology when sponsored by for profit organizations, which shall receive ownership to all data and results stemming from the sponsored research, shall need a commercial license agreement from Vectalys in order to use the Vectalys’ Technology or the product obtained by the Vectalys’ technology. Please contact Vectalys for information on purchasing a license to use these products for commercial purposes: Parc Technologique du Canal, Bâtiment Canal Biotech II, 3, rue des satellites, 31400 Toulouse (France), TEL: +33(0)5 61 28 70 75, EMAIL: sandy.darrigan@vectalys.com.
263	Lentikat ™ System (SIN technology) This product including the Lentiviral Technology (based upon the lentikat™ system) is sold pursuant to a licensing arrangement between Vectalys and Life Technologies Corporation. The purchase price of this product includes limited, nontransferable rights under U.S. Patent Nos. 5,994,136 and 6,165,782 and their foreign equivalents, excluding, however, any patents or patent equivalents filed with contracting states to the European Patent Convention or any extension states thereof, to use the product for internal research purposes directed to target validation and cellular screening only. Use of this technology for gene therapy applications or bioprocessing other than for non-human research use requires a license from GBP IP, LLC. The purchase of this product conveys to the buyer the non-transferable right to use the product in internal research directed to target validation and cellular screening conducted by the buyer (whether the buyer is an academic or for-profit entity), including such applications in laboratory animals. The buyer cannot sell or otherwise transfer (a) this product (b) its components or (c) materials made using this product or its components to a third party or otherwise use this product or its components or materials made using this product or its components for Commercial Purposes. The buyer may transfer information or materials made through the use of this product to a scientific collaborator, provided that such transfer is not for any Commercial Purpose, and that such collaborator agrees in writing (a) not to transfer such materials to any third party, and (b) to use such transferred materials and/or information solely for research as set forth herein and not for Commercial Purposes. Commercial Purposes means any activity by a party for consideration and may include, but is not limited to: (1) use of this product or its components in manufacturing; (2) use of this product or its components to provide a service, information, or data; (3) use of this product or its components for therapeutic, diagnostic or prophylactic purposes; or (4) resale of this product or its components, whether or not such product or its components is resold for use in research. For information on purchasing a license to this product for purposes other than those permitted in this Label License, contact Out-Licensing, Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, California 92008. Phone (760) 603-7200. Email: outlicensing@lifetech.com.
264	cPPT Element cPPT Element and its use are covered by one or more patents: FR9805197 and US 60/158387 and/or other pending foreign patent applications licensed to Vectalys. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot disclose information, sell or otherwise transfer this product, its components or materials made using this product or its components to a third party or otherwise use this product or its components or materials made using this product or its components for any commercial purposes. If the buyer is not willing to accept the limitations of this limited use statement, Vectalys is willing to accept return of the product with a full refund. For information on purchasing a license to the DNA-Flap technology for purposes other than research, contact the Transfer of Technology Office, Institut Pasteur, 28 rue du Docteur Roux, 75 724 Paris Cedex 15 (www.pasteur.fr).
268	cPPT Element cPPT Element and its use are covered by one or more patents: FR9805197 and US 60/158387 and/or other pending foreign patent applications licensed to Vectalys. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot disclose information, sell or otherwise transfer this product, its components or materials made using this product or its components to a third party or otherwise use this product or its components or materials made using this product or its components for any commercial purposes. If the buyer is not willing to accept the limitations of this limited use statement, Vectalys is willing to accept return of the product with a full refund. For information on purchasing a license to the DNA-Flap technology for purposes other than research, contact the Transfer of Technology Office, Institut Pasteur, 28 rue du Docteur Roux, 75 724 Paris Cedex 15 (www.pasteur.fr).
269	For Research Use Only. Not for diagnostics. Not for use in diagnostic procedures. Product is covered by patents and patent applications owned by Exiqon A/S.
270	This product is covered by U.S. Patent No. 9,410,173 and other pending patent applications in the United States and foreign jurisdictions. For further information, please contact a Takara Bio USA, Inc. licensing representative by e-mail at licensing@takarabio.com.
272	This product (“Product”) and its use, is the subject of U.S. Patents 8,697,359 and 8,771,945 and pending U.S. Patent applications. The purchase of the Product conveys to the buyer the non-transferable right to use Product(s) purchased from Takara Bio USA, Inc. or its Affiliates, and any progeny, modification or derivative of a Product, or any cell or animal made or modified through use of a Product, or any progeny, modification or derivative of such cell or animal (“Related Material”), solely for research conducted by the buyer in accordance with all of the following requirements. No right is given to use this Product or Related Material for any other purpose, including, but not limited to, use in drugs, in vitro diagnostic purposes, therapeutics, or in humans. The buyer shall not sell or otherwise transfer Products (including without limitation any material that contains a Licensed Product in whole or part) or any Related Material to any other person or entity, or use Products or any Related Material to perform services for the benefit of any other person or entity, (ii) the buyer shall use only the purchased amount of the Products and components of the Products, and shall use any Related Material, only for its internal research and not for (a) the practice, performance or provision of any method, process or service, or (b) the manufacture, sale, use, distribution, disposition or importing of any product, in each case (a) or (b) for consideration, or on any other commercial basis (“Commercial Purpose”), (iii) the buyer shall use Licensed Products and any Related Material in compliance with all applicable laws and regulations, including without limitation applicable human health and animal welfare laws and regulations, and (iv) the buyer shall indemnify, defend and hold harmless MIT, Harvard and The Broad and their current and former trustees, directors, officers, faculty, affiliated investigators, students, employees, and agents and their respective successors, heirs and assigns (“Indemnitees”), against any liability, damage, loss, or expense (including without limitation reasonable attorneys’ fees and expenses) incurred by or imposed upon any of the Indemnitees in connection with any claims, suits, investigations, actions, demands or judgments arising out of or related to the exercise of any rights granted to the buyer, or any breach of the rights granted hereunder by the buyer.
273	This product is covered by U.S. Patent Nos. 9,459,188 and/or 10,207,229, exclusively licensed to Takara Bio USA, Inc.
275	SMART-Seq2 Technology. This product is sold under exclusive license from Ludwig Institute of Cancer Research, Ltd. and is covered by Japanese Patent No. 6336080, US Patent No. 10266894, pending U.S. patent application, and/or pending claims of foreign counterparts. For license information, please contact a Takara Bio USA, Inc. licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com.
325	Patent pending. For further information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
326	This product is protected by U.S. Patents 7,803,550; 8,399,199; 8,728,737, 9,598,727, 10,196,686, 10,208,337 and corresponding foreign patents. Additional patents are pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
328	This product is protected by U.S. Patents 8,206,913 and corresponding foreign patents. Additional patents are pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
329	This product is protected by one or more of these U.S. Patents 9,132,427, 9,909,171, 9,447,925, 9,951,381 and/or corresponding foreign patents. Additional patents are pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
330	This product is the subject of a technology license agreement for internal research use only. Use of this product other than for research use may require additional licenses. Information on license restrictions or for uses other than research may be obtained by contacting licensing@takarabio.com.
347	This product is protected by U.S. Patents 9,895,665, 10,195,569 and foreign counterparts and/or additional U.S. and foreign patents pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
350	This product is protected by one or more of these U.S. Patents 7,622,296, 9,909,171, 9,132,427, 9,228,933 or 9,951,381, and corresponding foreign patents. Additional patents are pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
352	LentiFlash Technology: This product is covered by the French pending patent application FR1554381 and the PCT application PCT/FR/051152. The purchase price of this product includes limited, nontransferable rights to use this product solely for internal research purposes. Please contact Vectalys for information on purchasing a license to use these products for commercial purposes: Parc Technologique du Canal, Bâtiment Canal Biotech II, 3, rue des satellites, 31400 Toulouse (France), TEL: +33(0)5 61 28 70 75, EMAIL: sandy.darrigan@vectalys.com.
353	LentiFlash Technology: This product is covered by the French pending patent application FR1554381 and the PCT application PCT/FR/051152. The purchase price of this product includes limited, nontransferable rights to use this product solely for internal research purposes. Please contact Vectalys for information on purchasing a license to use these products for commercial purposes: Parc Technologique du Canal, Bâtiment Canal Biotech II, 3, rue des satellites, 31400 Toulouse (France), TEL: +33(0)5 61 28 70 75, EMAIL: sandy.darrigan@vectalys.com.
383	This product is covered by the claims of US patent No. 9422599.
384	This product is protected by U.S. Patents 7,803,550; 8,399,199; 9,598,727, 10,196,686, 10,208,337, and 10,155,942 and corresponding foreign patents. Additional patents are pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
385	This product is protected by U.S. Patents 7,803,550, 8,399,199, 8,728,737, and 9,598,727 and corresponding foreign patents. Additional patents are pending. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
388	This product is protected by Canadian Patent No. 2921603 and Japanese Patent Nos. 6336080 and 6603699 and corresponding US and foreign pending patents. For further license information, please contact a Takara Bio USA licensing representative by email at licensing@takarabio.com.
391	LIMITED USE LABEL LICENSE: RESEARCH USE ONLY Notice to Purchaser: This product is the subject to a license granted to Takara Bio USA, Inc. and its Affiliates from Caribou Biosciences, Inc., and this product is transferred to the end-user purchaser (“Purchaser”) subject to a “Limited Use Label License” conveying to the Purchaser a limited, non-transferable right to use the product, solely as provided to Purchaser, together with (i) progeny or derivatives of the product generated by the Purchaser (including but not limited to cells), and (ii) biological material extracted or derived from the product or its corresponding progeny or derivatives (including but not limited to cells) (collectively, the product, and (i) and (ii) are referred to as “Material”) only to perform internal research for the sole benefit of the Purchaser. The Purchaser cannot sell or otherwise transfer Material to a third party or otherwise use the Material for any Excluded Use. “Excluded Use” means any and all: (a) commercial activity including, but not limited to, any use in manufacturing (including but not limited to cell line development for purposes of bioproduction), product testing, or quality control; (b) preclinical or clinical testing or other activity directed toward the submission of data to the U.S. Food and Drug Administration, or any other regulatory agency in any country or jurisdiction where the active agent in such studies comprises the Material; (c) use to provide a service, information, or data to a third party; (d) use for human or animal therapeutic, diagnostic, or prophylactic purposes or as a product for therapeutics, diagnostics, or prophylaxis; (e) activity in an agricultural field trial or any activity directed toward the submission of data to the U.S. Department of Agriculture or any other agriculture regulatory agency; (f) high throughput screening drug discovery purposes (i.e., the screening of more than 10,000 experiments per day) as well as scale-up production activities for commercialization; (g) modification of human germline, including editing of human embryo genomes (with the sole exception of editing human embryonic stem (ES) cell lines for research purposes) or reproductive cells; (h) self-editing; and/or (i) stimulation of biased inheritance of a particular gene or trait or set of genes or traits (“gene drive”). It is the Purchaser’s responsibility to use the Material in accordance with all applicable laws and regulations. For information on obtaining additional rights, including commercial rights, please contact licensing@cariboubio.com or Caribou Biosciences, Inc., 2929 7th Street, Suite 105, Berkeley, CA 94710 USA, Attn: Licensing.
C001	This product is manufactured and sold by Takara Bio Europe AB based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product and its use are covered by one or more claims of patents owned by WARF, including U.S. Patent Nos. 7,514,260, 7,439,064, 7,005,252, 7,217,569 and their foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C004	This product is manufactured and sold by Takara Bio Europe AB based on a commercial license to certain intellectual property rights held by GE Healthcare UK Limited (“GE”). This product and its use are covered by one or more claims of U.S. Patent No. 9,074,181 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe AB based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities wishing to use this product are required to obtain a license from Takara Bio Europe AB. For license information, please contact us by phone: +46 (0) 31 7580900 or e-mail: info-cellartis@takarabio.com. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com
C007	This product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) (“Takara”) under a license from ViaCyte Inc. (“ViaCyte”). This product is covered by one or more claims of patents owned by ViaCyte, including WO2005063971, WO2006017134, WO2006071911, WO2005116073 and WO200616999, and their foreign counterparts. The use of this product is strictly limited to purchaser's own internal research. Purchaser has no right to use this product or its components in humans for any purposes including but not limited to diagnostics, therapeutics, or clinical trials. Purchaser has no right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact Takara. No express or implied license is granted to the purchaser.
C008	This product is manufactured and sold by Takara Bio Europe AB based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of patents owned by WARF, including U.S. Patent Nos. 7,514,260, 7,439,064, 7,005,252, 7,217,569, 7,029,913, 8,273,569, and their foreign counterparts. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
C011	This service is performed by Takara Bio Europe AB based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). The deliverables and their use are covered by one or more claims of patents owned by WARF, including U.S. Patent Nos. 7,514,260, 7,439,064, 7,005,252, 7,217,569, and their foreign counterparts. The purchase of this service conveys to the buyer the non-transferable right to use the deliverables for their intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use the deliverables or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer the deliverables to a third party regardless of whether or not compensation is received. Purchasers wishing to use the deliverables for purposes other than internal research use should contact us.
C013	This service is performed by Takara Bio Inc. and/or its affiliate(s) (“Takara”) under a license from ViaCyte Inc. (“ViaCyte”). This product is covered by one or more claims of patents owned by ViaCyte, including WO2005063971, WO2006017134, WO2006071911, WO2005116073 and WO2006016999, and their foreign counterparts. The use of the deliverables is strictly limited to purchaser's own internal research. Purchaser has no right to use the deliverables or their components in humans for any purposes including but not limited to diagnostics, therapeutics, or clinical trials. Purchaser has no right to resell or transfer the deliverables to a third party regardless of whether or not compensation is received. Purchasers wishing to use the deliverables for purposes other than internal research use should contact Takara. No express or implied license is granted to the purchaser.
C015	This service is performed by Takara Bio Europe AB based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of patents owned by WARF, including U.S. Patent Nos. 7,514,260, 7,439,064, 7,005,252, 7,217,569, 7,029,913, 8,273,569 and their foreign counterparts. The purchase of this service conveys to the buyer the non-transferable right to use the deliverables for their intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use the deliverables or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer the deliverables to a third party regardless of whether or not compensation is received. Purchasers wishing to use the deliverables for purposes other than internal research use should contact us.
C018	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities wishing to use this product are required to obtain a license from Takara Bio Europe AB. For license information, please contact us by phone: +46 (0) 31 7580900 or e-mail: info-cellartis@takarabio.com. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human ES Cell Line license agreement to us. For details please contact licensing@takarabio.com.
K11	This product and its use are the subject to one or more of the following U.S. Pat. 8,093,042 and foreign equivalents. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot disclose information, sell or otherwise transfer this product, its components or materials made using this product or its components to a third party or otherwise use this product or its components or materials made using this product or its components for any commercial purposes. If the buyer is not willing to accept the limitations of this limited use statement, Takara Bio USA is willing to accept return of the product with a full refund. For information on purchasing a license to the DNA-Flap technology for purposes other than research, contact the Transfer of Technology Office, Institut Pasteur, 28 rue du Docteur Roux, 75 724 Paris Cedex 15 (www.pasteur.fr).
K13	The RCFPs (including DsRedExpress, DsRedExpress2, and E2-Crimson) are covered by one or more of the following U.S. Patent Nos. 7,166,444; 7,157,565; 7,217,789; 7,338,784; 7,338,783; 7,537,915; 6,969,597; 7,150,979; 7,442,522 and 8,012,682.
K22	Living Colors Fluorescent Protein Products. Not-For-Profit Entities: Orders may be placed in the normal manner by contacting your local representative or Takara Bio USA, Inc. Customer Service. Any and all uses of this product will be subject to the terms and conditions of the Non-Commercial Use License Agreement (the “Non-Commercial License”), a copy of which can be found below. As a condition of sale of this product to you, and prior to using this product, you must agree to the terms and conditions of the Non-Commercial License. Under the Non-Commercial License, Takara Bio USA, Inc. grants Not-For-Profit Entities a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial scientific research use only. Such license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to third parties. No modifications to the product may be made without express written permission from Takara Bio USA, Inc. Any other use of this product requires a different license from Takara Bio USA, Inc. For license information, please contact a licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com. For-Profit Entities wishing to use this product are required to obtain a license from Takara Bio USA, Inc. For license information, please contact a licensing representative by phone at 650.919.7320 or by e-mail at licensing@takarabio.com.
K68	This product is covered by U.S. Patent No. 7,176,298.
L4	This product is for measurement of amplification detection for research use only in life sciences research, industrial and environmental testing (including food industry, but excluding bio-terrorism and bio-warfare), non-human animal diagnostic testing, forensic testing and providing services to third parties who do not use the services for the purpose of (a) providing patient management or care, and in which the results of such services are not included in patient records and (b) providing bio-terrorism or bio-warfare testing; and specifically excluding, without limitation: (I) any human clinical, therapeutic or diagnostic uses and animal clinical and therapeutic uses (including any use of the results of any testing performed with any product for patient management or care, or the use of the results of the services for patient management or care) and (II) any research or services where the results of any test or assay are used for patient management, care or otherwise in making therapeutic or treatment decisions for a patient. A portion of this product is subject to proprietary rights of Epoch Biosciences, Inc. and are made and sold under license from Epoch Biosciences, Inc. under the patents and patent applications (US20020155484, WO0142505, WO02099141, US09/876,830 and corresponding patents issued in other countries). There is no implied license for commercial use with respect to this product. A license must be obtained directly from Epoch Biosciences, Inc. with respect to any proposed commercial use of this product, and “commercial use” includes but is not limited to (A) the sale, lease, license or other transfer of this product or any material derived or produced from it, (B) the sale, lease, license or other grant of rights to use this product or any material derived or produced from it, and (C) the sale, lease, license or other transfer of kits which include this product.
L20	This product is covered by the claims of U.S. Patent No. 8,183,011 and their foreign counterpart patent claims and pending patents, assigned to Rutgers, The State University of New Jersey.
L21	This product is covered by the claims of U.S. Patent No. 6,451,595 and their foreign counterpart patent claims.
L23	This product is covered by the claims of U.S. Patent No. 6,852,833 and its foreign counterpart patent claims. This product is manufactured and sold by Takara Bio Inc. under licenses from National Agriculture and Food Research Organization and EZAKI GLICO CO., LTD.
L31	This product is the subject of U.S. Patent No. 8,216,833 and its foreign counterparts.
L33	This product is covered by the claims of U.S. Patent No. 7,326,779 and its foreign counterpart patent claims.
L34	This product is covered by the claims of U.S. Patent No. 7,264,959 and its foreign counterpart patent claims.
L39	1. Brevibacillus Expression System-related products were developed and manufactured by Higeta Shoyu Co., Ltd. and sold by TAKARA BIO INC. 2. The use of this product is allowed for research use only. 3. All rights of intellectual property related to this product are owned by Higeta Shoyu Co., Ltd.
L42	This product is sold by Takara Bio Inc. under license from Fuso Pharmaceutical Industries, Ltd. and Osaka Prefecture University. This product is covered by the claims of U.S. patent 7,563,594 and its foreign counterparts.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
L58	The Products are manufactured and patented by Cyanagen s.r.l and protected by US7803573; EP1962095; US7855287; EP1950207; CA2742025; EP2405016 and foreign equivalents and other pending patents.
L62	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141, 9,714,433, and 10,385,407 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This custom service is provided by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of iPSCs produced by this service (hereinafter referred to as the "custom iPSCs") is strictly limited to customer’s own internal research. Customer cannot have any right to use the custom iPSCs in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. There is no right to resell or transfer the custom iPSCs to a third party regardless of whether or not compensation is received. The use of custom iPSCs is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of the custom iPSCs-derived embryos into human or animal individuals, 2) Custom iPSCs transplantation into human embryos, 3) Custom iPSCs transplantation into human fetuses, and 4) Production of human embryos using the custom iPSCs-derived germ cells. Customers wishing to use the custom iPSCs for purposes other than internal research use should contact us. No express or implied license is granted to the customer. Any use of the custom iPSCs for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of custom iPSCs: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from the custom iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from the custom iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from the custom iPSCs). A patent license to use the custom iPSCs and the use of the differentiated cells from the custom iPSCs for screening compounds may also be granted from Takara Bio Inc.
L67	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141, 9,714,433, and 9,938,585 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This Product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) based on a patent license from iPS Academia Japan, Inc. No express or implied license is granted to the purchaser. "Product" means the differentiated cells manufactured and sold by Takara Bio Inc. "Internal research purpose" means the use of this Product as a tool of internal research for the sole benefit of the purchaser or purchaser's contract research customer, (including screening of compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use), provided, however, that the following activities using this Product are strictly prohibited and expressly excluded from Internal research purposes: With the exemption for academic and non-commercial clinical research done by non-profit institutions; 1) Administration of this Product to humans. 2) Use of this Product for the diagnostic testing, prevention, or treatment of human and/or animal diseases. 3) Use of this Product in studies involving administration to humans for cell therapy, regenerative medicine etc. Purchaser may use this Product for its own Internal research purposes. Purchaser shall not use the Products for its commercial purposes. Notwithstanding the foregoing, the purchaser of this Product may provide third parties with contract research services by using this Product only for such third party's Internal research purposes.
L69	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141, 9,714,433, and 9,938,585 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This custom service is provided by Takara Bio Inc. and/or its affiliate(s) based on a patent license from iPS Academia Japan, Inc. No express or implied license is granted to the purchaser. "Product" means the customized differentiated cells manufactured and sold by Takara Bio Inc. "Internal research purpose" means the use of this Product as a tool of internal research for the sole benefit of the purchaser or purchaser's contract research customer, (including screening of compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use), provided, however, that the following activities using this Product are strictly prohibited and expressly excluded from Internal research purposes: With the exemption for academic and non-commercial clinical research done by non-profit institutions; 1) Administration of this Product to humans. 2) Use of this Product for the diagnostic testing, prevention, or treatment of human and/or animal diseases. 3) Use of this Product in studies involving administration to humans for cell therapy, regenerative medicine etc. Purchaser may use this Product for its own Internal research purposes. Purchaser shall not use the Products for its commercial purposes. Notwithstanding the foregoing, the purchaser of this Product may provide third parties with contract research services by using this Product only for such third party's Internal research purposes.
L71	This service is performed by Takara Bio Inc. and/or its affiliate(s) based on a commercial license to certain intellectual property rights held by ID Pharma Co.,Ltd. The deliverables and their use are covered by one or more claims of patents owned by ID Pharma, including PCT/JP00/03195, PCT/JP2009/062911, PCT/JP2011/069588 and PCT/JP2014/75248 and their foreign counterparts. The purchase of this service conveys to the buyer the non-transferable right to use the deliverables for their intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use the deliverables or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer the deliverables to a third party regardless of whether or not compensation is received. Purchase does not include any right to provide Contract Manufacturing Service with the use of the deliverables to a third party, unless a license is negotiated with ID Pharma Co., Ltd. Purchasers wishing to use the deliverables for purposes other than internal research use should contact us.
L72	This product is manufactured and sold by Takara Bio Inc. based on a license to Cellectis SA. The use of this product is strictly limited to purchaser's own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
M5	This product is covered by the claims of JP Patent No. 4857260.
M40	This product is covered by the claims of U.S. Patent No. 7,422,888 and its foreign counterpart patent claims.
M54	This product is covered by the claims of U.S. Patent Nos. 7,704,713 and its foreign counterparts.
M69	This product is covered by the claims of Japanese Patent No. 4406566 and its foreign counterpart patent claims.
M69a	Before purchasing this product, you must submit a completed copy of the RetroNectin® (GMP) Ordering Sheet to us.
M69b	Before purchasing this product, you must submit a completed copy of the Anti-CD3 mAb (GMP) Order Check Sheet to us.
M76	This product is covered by the claims of Japanese Patent No. 5280916.
M81	This product is the subject of the claims of JP patent No.5887078.
M82	This product is covered by the claims of Japanese patent No. 6029636 and its foreign counterparts.
M83	This product is the subject of the claims of US patent No. 9422576 and its foreign counterparts.
M84	This product is the subject of the claims of US patent No. 10072250 and its foreign counterparts.
M85	This product is the subject of the claims of US patent No. 10161011 and its foreign counterparts.
M86	This product is covered by the claims of U.S. Patent No. 9,850,498 and its foreign counterpart patent claims. Orders may be placed in the normal manner by contacting your local representative or Takara Customer Service. Any and all uses of this product will be subject to Purchaser's Agreement to the Terms and Conditions of Sale (hereinafter "DOCUMENT"), a copy of which can be found below. As a condition of sale of this product to you, and prior to using this product, you must agree to the provisions described in the DOCUMENT. Use of this product other than granted in the DOCUMENT requires a different license from Takara Bio Inc. For license information, please contact a licensing representative by e-mail at bio-licensing@takara-bio.co.jp.
M87	This product is the subject of the pending JP patent application and its foreign counterparts.
M88	This product is covered by the claims of US Patent No. 10415020.

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