EpiCypher
Advancing epigenetics research with single-cell solutions
Dive deeper into gene regulation mechanisms with new epigenomic research tools
EpiCypher 2025 brought together key decision makers, technology users, and leaders in the chromatin and epigenetics disciplines to address important issues encountered in biologial and clinical research. We presented a featured talk and technology poster that included a sneak peek of Shasta CUT&Tag, our upcoming single-cell epigenetics assay that facilitates high-throughput epigenetic analysis and drug discovery.
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Featured talk
Dissecting gene regulatory programs through single-cell mapping of histone modifications
In this talk, Dr. Andrew Farmer discussed the next generation of single-cell solutions, including Shasta CUT&Tag, the first high-throughput single-cell CUT&Tag (scCUT&Tag) method. By combining the Takara Bio Shasta Single Cell System and scCUT&Tag, Shasta CUT&Tag enables researchers to profile histone modification patterns in thousands of individual cells from a single sample. This automated, single-cell approach to CUT&Tag provides a powerful tool for gene regulatory studies and epigenetics-based drug discovery research.
Technology poster
Profiling histone modifications in single cells to gain insight into the effects of epigenetic drug treatment on tumor cells
With this poster, Dr. Andrew Farmer presented a novel, high-throughput single-cell CUT&Tag (scCUT&Tag) method for complex epigenetic analysis, which enables discovery of gene regulatory changes for large samples at single-cell resolution. The automated Shasta CUT&Tag method applies the Takara Bio Shasta Single Cell System in conjunction with EpiCypher's CUT&Tag assay to profile histone modification patterns in thousands of individual cells and characterize global, cell type-specific acetylation patterns in A549 cells following epigenetic drug treatment.
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