T-cell transduction and culture
RetroNectin reagent is the gold standard transduction enhancer for retroviral/lentiviral gene transfer to hematopoietic cells and holds great promise in clinical applications. RetroNectin GMP grade has been used in over 40 clinical trials around the world. RetroNectin reagent promotes colocalization of lentivirus or retrovirus with target cells to dramatically enhance transduction efficiency, and it is highly effective for a variety of human cell lines. Additionally, RetroNectin reagent is an effective coating matrix for expanding ex vivo lymphocytes. It has been shown to increase the expansion of naïve CD8+ T cells from peripheral blood mononuclear cells (PBMCs) and to improve the expansion and post-transplant persistence of genetically modified T cells.
Overview of RetroNectin reagent
T-cell related products
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