Why use the Xfect RNA Transfection Reagent to transfect siRNA oligos?
- It's effective—get better knockdown than with the leading competitor
- It's easy—no optimization necessary
- It's nontoxic—Xfect won't kill your cells
Effective gene silencing using transfected siRNA oligos
Having good siRNA oligos is not enough if you can't deliver those siRNAs effectively since your experiment will fail. The Xfect RNA Transfection Reagent was developed to maintain a very low cytotoxicity profile while delivering high rates of gene silencing. The ratio of oligo to reagent is pre-optimized, so you don't have to waste time on preliminary experiments. Transfecting siRNA with Xfect RNA Transfection Reagent has been shown to result in successful knockdown, e.g., a 95% decrease in luciferase activity (Figure 1).