Gene editing tools and information
CRISPR/Cas9 comprises a set of powerful gene editing tools that are revolutionizing the field of biology, with the promise to create new research models for disease and to, in the future, perhaps prevent or cure disease. These tools are providing unprecedented efficiency and precision to knock out genes in living mammalian cells and also the power to knock in and create novel sequences using homology directed repair (HDR).
The links below include introductions to the technology and some selection guides to help researchers choose the right products for their applications.
Introduction to CRISPR/Cas9
Overview of CRISPR/Cas9 system for genome editing.
Gene editing product finder
Use this gene editing product finder to quickly locate kits for screening, delivery, and downstream assays.
Tools for successful CRISPR/Cas9 genome editing
An overview of tools available for each step in a successful genome editing workflow.
How to design sgRNA sequences
Learn how to design sgRNA sequences for successful gene editing.
sgRNA design tools
Browse a collection of sgRNA design tools for Cas9-based genome editing experiments.
Screening for effective guide RNAs
Before delivering sgRNA to your cells, use a novel in vitro assay to get accurate predictions of sgRNA cleavage efficiency.
Customer data for gene editing products
See data generated from customers using our Guide-it products.
Gene editing posters
Gene editing posters presented at various scientific conferences.
Oligo design tool for SNP screening
Use our simple online tool to rapidly design assay-specific oligos for SNP detection with the Guide-it Knockin Screening Kit.
Gene editing of CD3+ T cells and CD34+ HSCs
Follow these protocols developed by our R&D team for easy CRISPR/Cas-based gene editing of immune cells.
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