Introduction to ICELL8 technology

An open and flexible platform for developing your high-throughput single-cell assays

The ICELL8 cx Single-Cell System and the original ICELL8 Single-Cell System (modular) are open platforms that enable the processing of hundreds of single cells or nuclei, irrespective of size or shape, and can process up to eight samples in parallel. This makes them suitable for performing replicates and eliminating batch effects.

The system takes advantage of imaging to distinguish single-cell-containing wells from wells that are empty or contain multiple cells (thereby decreasing background) and provides a simple, automated workflow:

• Cells are dispensed into a patented 5,184-nanowell SmartChip.
• Images are created for every nanowell in the chip.
• The acquired images are processed using the included CellSelect Software, with >85% accuracy identifying nanowells that contain only a single cell.
• Library preparation reagents are selectively dispensed, dictated by the user, to the wells containing single cells, as identified by CellSelect Software or manually selected by the user.
• The preinstalled CELLSTUDIO Software allows users to design custom, high-throughput NGS or single-cell applications on a nanoliter scale.

Explore the links below for an overview of ICELL8 technology, technical specifications for the ICELL8 cx system, application notes, webinars, and more.