We use cookies to improve your browsing experience and provide meaningful content. Read our cookie policy. Accept
  •  Customer Login
  • Register
  •  View Cart (0)
  •  Customer Login
  • Register
  •  View Cart (0)

  • Products
  • Learning centers
  • Services & Support
  • Areas of interest
  • About

Close

  • ‹ Back to Lentivirus
  • Lenti-X FAQs
  • Lentiviral workflow
  • Lentiviral products guide
  • Lentivirus biosafety
  • Lentiviral tips
  • Lentiviral vectors
  • Lenti-X packaging
  • Lenti-X Concentrator
  • Lentiviral titration
  • Lenti-X GoStix Plus video protocols
  • Lenti-X GoStix Plus FAQs
  • Rapid lentivirus titration by p24 ELISA
  • Lentiviral particles
  • Lentiviral particles—fluorescent
  • Lentiviral particles webinar
  • Lentiviral particles FAQs
Selection guides Virus kits: product finder tool
Tools for recombinant lentivirus production and evaluation Lentivirus product catalog
Home › Learning centers › Gene function › Viral transduction › Lentivirus › Lentivirus biosafety

Viral transduction

  • Recombinant virus comparison
  • Product finder
  • Transduction posters
  • Lentivirus
    • Lenti-X FAQs
    • Lentiviral workflow
    • Lentiviral products guide
    • Lentivirus biosafety
    • Lentiviral tips
    • Lentiviral vectors
    • Lenti-X packaging
    • Lenti-X Concentrator
    • Lentiviral titration
    • Lenti-X GoStix Plus video protocols
    • Lenti-X GoStix Plus FAQs
    • Rapid lentivirus titration by p24 ELISA
    • Lentiviral particles
    • Lentiviral particles—fluorescent
    • Lentiviral particles webinar
    • Lentiviral particles FAQs
  • Retrovirus
    • Retroviral products
    • Retro-X FAQs
    • Retro-X packaging
    • Retro-X Concentrator
  • Adeno-associated virus
    • AAV workflow
    • AAV delivery in vivo
    • AAV products
    • AAV FAQs
    • AAV2 purification video
    • AAVpro Concentrator overview
  • Adenovirus
    • Adenoviral FAQs
    • Adenoviral products
    • Fastest, easiest adenoviral system ever
    • Tet-inducible adenovirus
    • Adenovirus purification kits
    • Adenovirus purification mega-scale
    • Adenovirus rapid titer
    • Adenoviral titration
New products
Need help?
Contact Sales
Selection guides Virus kits: product finder tool
Tools for recombinant lentivirus production and evaluation Lentivirus product catalog

Comments on lentivirus biosafety

Lentiviral vector safety information

Your safety is our number one priority

Lentiviral safety information

The biosafety issues associated with using recombinant lentiviral vectors, i.e., the potential for producing oncogenic viruses or replication-competent lentivirus (RCL), can be greatly mitigated by carefully considering the nature of the transgene insert and by ensuring that viral replication is restricted to specific packaging cells that provide these essential functions, in trans. Lentiviral vectors can thus be used safely and are extremely useful tools for one-way transfers of exogenous genetic material into target cells.

Uncoupled gag and pol with 4th-generation packaging

Most commercially available lentiviral packaging systems are 3rd-generation versions that utilize split genes to provide the viral packaging elements on individual plasmids that physically separate the viral envelope sequence, env (usually VSV-G), from the gag-pro-pol sequences. These split-gene packaging strategies reduce the risk of generating RCL because multiple recombination events are necessary to create a virus that harbors the sequences required for independent replication. Takara Bio's Lenti-X packaging system also uses a split-gene packaging strategy but adds another level of reassurance by further uncoupling pol (RT and IN) from gag-pro. The result is that gag, pol, and env reside on three physically distinct entities, rather than the standard two (Figure 1). This approach further reduces the possibility of creating RCL to a level below that of standard 3rd generation packaging systems, because extra recombination events are required to create such viruses. In fact, the emergence of RCL is undetectable from systems using this approach (Wu et al. 2000). These improvements significantly increase the safety profile of our Lenti-X Single Shots Packaging System.

Lentivirus vector components

Takara Bio's Lenti-X packaging system consists of 5 separate components (Panel A), mixed in proprietary proportions for optimized packaging activity. The separation of the gag, pol, and env genes effectively reduces the incidence of RCL (Wu et al. 2000). Other 3rd-generation systems (Panel B) which do not contain separate gag and pol sequences have higher RCL-generating potential. High levels of expression of essential viral components are driven by the Tet-Off and Tat transactivators, resulting in high titers of virus. The pol gene is fused to vpr to ensure transport of the reverse transcriptase/integrase protein into the recombinant viral particle. Not all vector elements are shown.

Lenti-X vector safety

Takara Bio's Lenti-X vectors contain less than one-third of the wild-type HIV-1 genome. These wild-type sequences mainly consist of the viral LTRs and packaging signal (see vector maps for detailed sequence information or see the vector selection guide). All essential replication genes have been completely removed and are instead supplied as separate DNA entities in the Lenti-X single shots packaging mix (described above).


Lentivirus usage and safety guidelines

The protocols supplied with Takara Bio's Lenti-X systems require the production, handling, and storage of infectious lentivirus. It is imperative to fully understand the potential hazards of, and necessary precautions for, the laboratory use of lentiviruses. The National Institutes of Health and Centers for Disease Control have designated recombinant lentiviruses as Level 2 organisms. Takara Bio advises that you contact your health and safety facilities for local guidelines and regulations, and strongly recommends that new users of all viral technologies receive training from experienced personnel.

For more details, download the NIH's "Biosafety Considerations for Research with Lentiviral Vectors," and check the NIH website for updated information.

NIH guidelines require the maintenance of a Biosafety Level 2 (BL-2) facility for work involving lentivirus and others like it. The VSV-G pseudotyped lentiviruses packaged from the HIV-1-based vectors described here are capable of infecting human cells. The viral supernatants produced by these lentiviral systems could, depending on your insert, contain a potentially hazardous recombinant virus. Similar vectors have been approved for human gene therapy trials, attesting to their potential ability to transfer and express genes in vivo.

For these reasons, due caution must be exercised in the production and handling of any recombinant lentivirus. The user is strongly advised not to create VSV-G pseudotyped lentiviruses capable of expressing known oncogenes.

For more information on Biosafety Level 2 agents and practices, download Biosafety in Microbiological and Biomedical Laboratories (BMBL), Fifth Edition (Revised December 2009), HHS Pub. No. (CDC) 21-1112. U.S. Department of Health and Human Services Centers for Disease Control and Prevention and NIH.

Summary of Biosafety Level 2 practices

The following information is a brief description of Biosafety Level 2. It is neither detailed nor complete. Details of the practices, safety equipment, and facilities that combine to produce a Biosafety Level 2 are available in the above publication. If possible, observe and learn the practices described below from someone who has experience working with lentiviruses.

Standard microbiological practices

  • Limit access to work area
  • Post biohazard warning signs
  • Minimize production of aerosols
  • Decontaminate potentially infectious wastes before disposal
  • Use precautions with sharps (e.g., syringes, blades)
  • Provide a biosafety manual defining any needed waste decontamination or medical surveillance policies

Safety equipment

  • Biological Safety Cabinet, preferably a Class II BSC/laminar flow hood (with a HEPA microfilter) used for all manipulations of agents that cause splashes or aerosols of infectious materials; exhaust air is unrecirculated
  • PPE: protective laboratory coats, gloves, face protection as needed

Facilities

  • Autoclave available for waste decontamination
  • Chemical disinfectants available for spills

Note: The components that make up the Lenti-X family of products are designed to work together as a system. Substituting components from other manufacturers or that users have developed in-house, may affect performance and or safety. We recommend that you utilize our complete system, however, if you do decide to use components other than those developed by Takara Bio, please carefully consider performance and safety implications.

References

Wu, X. et al. Development of a novel trans-lentiviral vector that affords predictable safety. Mol. Ther. 2, 47–55 (2000). 


Related product pages

  • Viral product finder tool
  • Lentiviral vectors
  • Premade lentiviral particles
  • Lentiviral packaging kits
  • Lentivirus titration kits
  • Lenti-X Concentrator
  • Lentivirus purification kits
  • Integration-site analysis
  • Transduction enhancers

Takara Bio USA, Inc.
United States/Canada: +1.800.662.2566 • Asia Pacific: +1.650.919.7300 • Europe: +33.(0)1.3904.6880 • Japan: +81.(0)77.565.6999
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. © 2019 Takara Bio Inc. All Rights Reserved. All trademarks are the property of Takara Bio Inc. or its affiliate(s) in the U.S. and/or other countries or their respective owners. Certain trademarks may not be registered in all jurisdictions. Additional product, intellectual property, and restricted use information is available at takarabio.com.

Takara Bio USA, Inc. (TBUSA, formerly known as Clontech Laboratories, Inc.) provides kits, reagents, instruments, and services that help researchers explore questions about gene discovery, regulation, and function. As a member of the Takara Bio Group, TBUSA is part of a company that holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Our mission is to develop high-quality innovative tools and services to accelerate discovery.

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES (EXCEPT AS SPECIFICALLY NOTED).

Support
  • Contact us
  • Technical support
  • Customer service
  • Shipping & delivery
  • Sales
  • Feedback
Products
  • New products
  • Special offers
  • Instrument & reagent services
  • Corporate development
Learning centers
  • NGS
  • Gene function
  • Stem cell research
  • Protein research
  • PCR
  • Cloning
  • Nucleic acid purification
About
  • Our brands
  • Careers
  • Events
  • Blog
  • Need help?
  • Announcements
  • Quality and compliance
  • That's Good Science!
Facebook Twitter  LinkedIn

©2019 Takara Bio Inc. All Rights Reserved.

Region - North America Privacy Policy Terms and Conditions Terms of Use

Top



  • Automation systems
  • SmartChip Real-Time PCR System, chips, and reagents
  • Apollo system
  • ICELL8 system and software
  • Next-generation sequencing
  • Single-cell RNA- and DNA-seq
  • RNA-seq
  • DNA-seq
  • Immune profiling
  • Real-time PCR
  • Real-time PCR kits
  • Reverse transcription prior to qPCR
  • RNA extraction and analysis for real-time qPCR
  • Stem cell research
  • Media and supplements
  • Stem cells and stem cell-derived cells
  • Human iPS cell gene editing systems
  • Nucleic acid purification
  • Plasmid purification kits
  • Genomic DNA purification kits
  • DNA cleanup kits
  • RNA purification kits
  • cDNA synthesis
  • cDNA synthesis kits
  • Reverse transcriptases
  • RACE kits
  • Purified cDNA & genomic DNA
  • Purified total RNA and mRNA
  • PCR
  • Most popular polymerases
  • High-yield PCR
  • High-fidelity PCR
  • GC rich PCR
  • PCR master mixes
  • Cloning
  • In-Fusion Cloning
  • Competent cells
  • Ligation kits
  • Restriction enzymes
  • Cell biology assays
  • Extracellular vesicle miniprep
  • Exosome isolation (cell culture)
  • Reporter systems
  • Apoptosis detection kits
  • Epigenetics
  • Signal transduction
  • Gene function
  • Gene editing
  • Fluorescent proteins
  • Viral transduction
  • T-cell transduction and culture
  • Tet-inducible expression systems
  • Transfection reagents
  • Protein research
  • Purification products
  • Two-hybrid and one-hybrid systems
  • Mass spectrometry reagents
  • Antibodies and ELISAs
  • Primary antibodies and ELISAs by research area
  • Fluorescent protein antibodies
  • New products
  • Special offers
  • Fluorescent protein plasmids
  • Capturem his-tagged purification sale
  • In-Fusion Cloning sale
  • qPCR promotion
  • Nucleic acid purification sale
  • Nucleic acid purification kit samples
  • Power medium promotion
  • CRISPR-Cas9 promotion
  • Lenti-X special offers
  • PCR samples
Alzheimer's disease research

Alzheimer's disease research

Alzheimer's disease (AD) affects ~5.8 million adults and is the sixth leading cause of death in the US alone. Over 400 AD clinical trials are currently under way, investigating the possibilities of immunotherapy, our microbiome, and inflammation as prospective therapeutic targets. We have a variety of best-in-class products that can help your AD research move forward.

See how our best-in-class solutions can help to advance your AD research

  • Automation systems
  • SmartChip Real-Time PCR System introduction
  • Apollo library prep system introduction
  • ICELL8 introduction
  • Next-generation sequencing
  • Selection guide
  • Product line overview
  • Technical notes
  • FAQs and tips
  • Webinars
  • Posters
  • Real-time PCR
  • Product finder
  • Reaction size guidelines for qPCR
  • Real-time PCR products brochure
  • Real-time PCR tutorial videos
  • Overview
  • Technical notes
  • FAQs
  • Stem cell research
  • Applications
  • Technical notes
  • Webinars
  • Videos
  • Protocols
  • Citations
  • Nucleic acid purification
  • Product finder
  • Plasmid purification
  • Genomic DNA purification
  • DNA/RNA cleanup and extraction
  • Automated DNA and RNA purification
  • RNA purification
  • Hard-to-lyse samples
  • cDNA synthesis
  • PCR
  • Citations
  • Selection guides
  • PCR enzyme brochure
  • Technical notes
  • PCR FAQs
  • Cloning
  • In-Fusion Cloning tools
  • In-Fusion Cloning guide
  • In‑Fusion Cloning FAQs
  • In‑Fusion Cloning tips
  • Choosing a seamless cloning method
  • Seamless cloning primer design
  • Cell biology assays
  • Extracellular vesicle isolation from biofluids
  • Gene function
  • Gene editing
  • Viral transduction
  • T-cell transduction and culture
  • Inducible systems
  • Transfection reagents
  • Fluorescent proteins
  • Protein research
  • Capturem rapid purification technology
  • Antibody purification
  • His-tag purification
  • Phosphoprotein and glycoprotein purification
  • Mass spectrometry digestion reagents
  • Matchmaker Gold yeast two-hybrid systems
  • Antibodies and ELISA
Capturem Trypsin for a rapid, efficient mass spectometry workflow at room temperature.

Speed up your mass spec workflow

Capturem Trypsin provides rapid, efficient, and complete digestion of protein samples, allowing an uninterrupted mass spectometry workflow at room temperature for downstream protein analysis. This product utilizes our novel Capturem technology in a spin column format with membrane-immobilized trypsin. Capturem Trypsin Columns may be used to completely digest protein samples in less than a minute with digestion efficiencies (protein coverage) comparable to or better than those obtained using in-solution trypsin digestion.

Capturem trypsin technology

  • Customer service
  • Sales
  • Shipping & delivery
  • Technical support
  • Website FAQs
  • Feedback
  • Trademarks
  • License statements
  • Vector information
  • Vector document overview
  • Vector document finder
  • Online tools
  • Business development
  • OEM, custom, and supply-chain solutions
  • In licensing
  • Out licensing
  • Submit a licensing request
  • Instrument & reagent services
  • Cell and gene therapy manufacturing services
  • Custom enzyme supply services
  • Instrument services
  • Stem cell services
  • Takara Bio affiliates & distributors
  • United States and Canada
  • China
  • Japan
  • Korea
  • Europe
  • India
  • Affiliates & distributors, by country
Takara Bio's award-winning GMP-compliant manufacturing facility in Kusatsu, Shiga, Japan.

Partner with Takara Bio!

Takara Bio is proud to offer GMP-grade manufacturing capabilities at our award-winning facility in Kusatsu, Shiga, Japan.

Learn more

  • Cancer research
  • Sample prep from FFPE tissue
  • Sample prep from plasma
  • Cancer biomarker discovery
  • Cancer biomarker quantification
  • Single cancer cell analysis
  • Cancer genomics and epigenomics
  • HLA typing in cancer
  • Gene editing for cancer therapy/drug discovery
  • Immunotherapy research
  • T-cell therapy
  • Antibody therapeutics
  • T-cell receptor profiling
  • TBI initiatives in cancer therapy
  • Alzheimer's disease research
  • Antibody engineering
  • Sample prep from FFPE tissue
  • Single-cell sequencing
Create a web account with us

Log in to enjoy additional benefits

Want to save this information?

An account with takarabio.com entitles you to extra features such as:

•  Creating and saving shopping carts
•  Keeping a list of your products of interest
•  Saving all of your favorite pages on the site*
•  Accessing restricted content

*Save favorites by clicking the star () in the top right corner of each page while you're logged in.

Create an account to get started

  • Announcements
  • Events
  • Calendar
  • Conferences
  • Speak with us
  • Careers
  • Quality statement
  • Our brands
  • Takara
  • Clontech
  • Cellartis
  • Our history
  • That's Good Science!
  • Season one
  • Season two
  • Season three
  • BioView blog
  • Automation
  • Cancer research
  • Career spotlights
  • Customer stories
  • Gene editing
  • Research news
  • Single-cell analysis
  • Stem cell research
  • Tips and troubleshooting
  • About our blog
  • Need help?
Best-in-class products, expert support, superior value

That's GOOD Science!

What does it take to generate good science? Careful planning, dedicated researchers, and the right tools. At Takara Bio, we thoughtfully develop best-in-class products to tackle your most challenging research problems, and have an expert team of technical support professionals to help you along the way, all at superior value.

Explore what makes good science possible

 Customer Login
 View Cart (0)
  • Home
  • Products
  • Learning centers
  • Services & Support
  • Areas of interest
  • Feedback
  • About
  •  Customer Login
  • Register
  •  View Cart (0)

Takara Bio USA, Inc. (TBUSA, formerly known as Clontech Laboratories, Inc.) provides kits, reagents, instruments, and services that help researchers explore questions about gene discovery, regulation, and function. As a member of the Takara Bio Group, TBUSA is part of a company that holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Our mission is to develop high-quality innovative tools and services to accelerate discovery.

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES (EXCEPT AS SPECIFICALLY NOTED).

Clontech, TaKaRa, cellartis

  • Products
  • Automation systems
  • Next-generation sequencing
  • Gene function
  • Stem cell research
  • Protein research
  • PCR
  • Cloning
  • Nucleic acid purification
  • Antibodies and ELISA
  • Cell biology assays
  • Real-time PCR
  • cDNA synthesis
  • Automation systems
  • SmartChip Real-Time PCR System, chips, and reagents
  • Apollo system
  • ICELL8 system and software
  • Next-generation sequencing
  • Single-cell RNA- and DNA-seq
  • RNA-seq
  • DNA-seq
  • Immune profiling
  • Epigenetics and small RNA sequencing
  • NGS accessories
  • Gene function
  • Gene editing
  • Fluorescent proteins
  • Viral transduction
  • T-cell transduction and culture
  • Tet-inducible expression systems
  • ProteoTuner protein control systems
  • iDimerize inducible protein interaction systems
  • Transfection reagents
  • Mammalian expression plasmids
  • Stem cell research
  • Media and supplements
  • Stem cells and stem cell-derived cells
  • Human iPS cell gene editing systems
  • Accessories
  • Protein research
  • Purification products
  • Two-hybrid and one-hybrid systems
  • Mass spectrometry reagents
  • Expression vectors & systems
  • Glycobiology
  • Antibodies and immunoprecipitation
  • SDS-PAGE & western blotting
  • Protein sequencing
  • Accessory enzymes
  • PCR
  • Most popular polymerases
  • Standard PCR
  • High-yield PCR
  • High-fidelity PCR
  • Fast PCR
  • Long-range PCR
  • GC rich PCR
  • Direct PCR
  • PCR master mixes
  • Custom business friendly and automation-ready solutions
  • Molecular diagnostic products
  • GMP-grade products
  • Application-specific PCR
  • Other PCR-related products
  • PCR thermal cyclers
  • Cloning
  • In-Fusion Cloning
  • Competent cells
  • Ligation kits
  • Mutagenesis kits
  • Ligation enzymes
  • Restriction enzymes
  • Modifying enzymes
  • Legacy cloning products
  • X-Gal and IPTG
  • Linkers, primers, and cloning vectors
  • Agarose gel electrophoresis
  • Nucleic acid extraction
  • Nucleic acid purification
  • Plasmid purification kits
  • Genomic DNA purification kits
  • DNA cleanup kits
  • RNA purification kits
  • RNA cleanup kits
  • Viral DNA and RNA purification kits
  • Accessories and components
  • Antibodies and ELISA
  • Primary antibodies and ELISAs by research area
  • Secondary antibodies
  • Antibody and ELISA accessories
  • Fluorescent protein antibodies
  • Cell biology assays
  • Extracellular vesicle miniprep
  • Exosome isolation (cell culture)
  • Reporter systems
  • Apoptosis detection kits
  • Epigenetics
  • Cell biology reagents
  • RNA interference
  • Cell-culture accessories
  • Signal transduction
  • Real-time PCR
  • Real-time PCR kits
  • Reverse transcription prior to qPCR
  • Real-time PCR primer sets
  • References and standards for qPCR
  • RNA extraction and analysis for real-time qPCR
  • Application-specific qPCR
  • cDNA synthesis
  • cDNA synthesis kits
  • Reverse transcriptases
  • RACE kits
  • Purified cDNA & genomic DNA
  • Purified total RNA and mRNA
  • cDNA synthesis accessories
  • Learning centers
  • Automation systems
  • Next-generation sequencing
  • Gene function
  • Stem cell research
  • Protein research
  • PCR
  • Cloning
  • Nucleic acid purification
  • Antibodies and ELISA
  • Cell biology assays
  • Real-time PCR
  • cDNA synthesis
  • Automation systems
  • SmartChip Real-Time PCR System introduction
  • Apollo library prep system introduction
  • ICELL8 introduction
  • Next-generation sequencing
  • Selection guide
  • Product line overview
  • Technical notes
  • Featured kits
  • Technology and application overviews
  • FAQs and tips
  • DNA-seq protocols
  • Webinars
  • Citations
  • Posters
  • Gene function
  • Gene editing
  • Viral transduction
  • T-cell transduction and culture
  • Inducible systems
  • Transfection reagents
  • Fluorescent proteins
  • Stem cell research
  • Applications
  • Technical notes
  • Posters
  • Webinars
  • Videos
  • Protocols
  • FAQs
  • Citations
  • Selection guides
  • Overview
  • Protein research
  • Capturem rapid purification technology
  • Antibody purification
  • His-tag purification
  • Other tag purification
  • Phosphoprotein and glycoprotein purification
  • Mass spectrometry digestion reagents
  • Matchmaker Gold yeast two-hybrid systems
  • Expression systems
  • PCR
  • Citations
  • Selection guides
  • PCR enzyme brochure
  • Technical notes
  • PCR FAQs
  • Go green with lyophilized enzymes
  • LA PCR technology
  • Cloning
  • In-Fusion Cloning tools
  • In-Fusion Cloning guide
  • In‑Fusion Cloning FAQs
  • In‑Fusion Cloning tips
  • Choosing a seamless cloning method
  • Seamless cloning primer design
  • In-Fusion Cloning applications collection
  • Efficient cloning for sgRNA/Cas9 plasmids
  • In-Fusion Cloning tech notes
  • In-Fusion Cloning webinars
  • In-Fusion Cloning citations
  • EcoDry reagents and sustainability
  • Mutagenesis with In-Fusion Cloning
  • Efficient multiple-fragment cloning
  • Sign up to stay updated
  • Traditional molecular cloning
  • Nucleic acid purification
  • Product finder
  • Plasmid purification
  • Genomic DNA purification
  • DNA/RNA cleanup and extraction
  • Parallel DNA, RNA & protein
  • Automated DNA and RNA purification
  • RNA purification
  • Hard-to-lyse samples
  • Antibodies and ELISA
  • Osteocalcin focus
  • Cell biology assays
  • Extracellular vesicle isolation from biofluids
  • Cell viability kits
  • Exosome isolation from cell culture
  • Mir-X microRNA quantification
  • Real-time PCR
  • Product finder
  • Reaction size guidelines for qPCR
  • Real-time PCR products brochure
  • Real-time PCR tutorial videos
  • Overview
  • Technical notes
  • FAQs
  • cDNA synthesis
  • Premium total and poly A+ RNA
  • SMARTer RACE 5'/3' Kit—advances in SMARTer PCR cDNA synthesis
  • Cloning antibody variable regions
  • Services & Support
  • Technical support
  • Shipping & delivery
  • Customer service
  • Sales
  • Website FAQs
  • Vector information
  • Online tools
  • Instrument & reagent services
  • Corporate development
  • Takara Bio affiliates & distributors
  • License statements
  • Trademarks
  • Vector information
  • Vector document overview
  • Vector document finder
  • Instrument & reagent services
  • Cell and gene therapy manufacturing services
  • Custom enzyme supply services
  • Instrument services
  • Stem cell services
  • Corporate development
  • OEM, custom, and supply-chain solutions
  • In licensing
  • Out licensing
  • Submit a licensing request
  • Takara Bio affiliates & distributors
  • United States and Canada
  • China
  • Japan
  • Korea
  • Europe
  • India
  • Affiliates & distributors, by country
  • Areas of interest
  • Cancer research
  • Immunotherapy research
  • Alzheimer's disease research
  • Cancer research
  • Sample prep from FFPE tissue
  • Sample prep from plasma
  • Cancer biomarker discovery
  • Cancer biomarker quantification
  • Single cancer cell analysis
  • Cancer genomics and epigenomics
  • HLA typing in cancer
  • Gene editing for cancer therapy/drug discovery
  • Immunotherapy research
  • T-cell therapy
  • Antibody therapeutics
  • T-cell receptor profiling
  • TBI initiatives in cancer therapy
  • Alzheimer's disease research
  • Antibody engineering
  • Sample prep from FFPE tissue
  • Single-cell sequencing
  • About
  • Manufacturing DSS Takara Bio India
  • Careers
  • Quality and compliance
  • Need help?
  • Our brands
  • Our history
  • Announcements
  • Our partners
  • BioView blog
  • That's Good Science!
  • Special offers
  • New products
  • Events
  • Our brands
  • Takara
  • Clontech
  • Cellartis
  • BioView blog
  • Automation
  • Cancer research
  • Career spotlights
  • Customer stories
  • Gene editing
  • Research news
  • Single-cell analysis
  • Stem cell research
  • Tips and troubleshooting
  • About our blog
  • That's Good Science!
  • Season one
  • Season two
  • Season three
  • Special offers
  • Buy Again and Save More on DSS Takara Bio India Manufactured products
  • Classic Campaign on Takara Bio and Macherey Nagel products
  • Fluorescent protein plasmids
  • Fluorescent protein plasmids
  • Capturem his-tagged purification sale
  • In-Fusion Cloning sale
  • qPCR promotion
  • Nucleic acid purification sale
  • Nucleic acid purification kit samples
  • Power medium promotion
  • CRISPR-Cas9 promotion
  • Lenti-X special offers
  • PCR samples
  • EOY Promo (DKK)
  • EOY Promo (EUR)
  • EOY Promo (SEK)
  • EOY Promo (CHF)
  • EOY Promo (GBP)
  • qPCR-RT promo (DKK)
  • RT-qPCR bundle promotion (EUR)
  • RT-qPCR bundle promotion (SEK)
  • RT-qPCR bundle promotion (CHF)
  • RT-qPCR bundle promotion (GBP)
  • Events
  • Calendar
  • Conferences
  • Speak with us
  • Products
  • Learning centers
  • Services & Support
  • Areas of interest
  • About