Early-access program: Spike-in controls

Get a sneak peek into our new products in development.   

At Takara Bio, we continuously innovate to provide you with the best solutions to facilitate your workflows.

An exogenous control is crucial to improving molecular assay workflows, as it reduces false negatives and false positives by:

• Validating extraction and amplification
• Acting as a PCR control
• Enabling improved quantification and normalization
• Ensuring a more standardized process

We have developed a new portfolio of spike-in controls for both DNA- and RNA-based qPCR workflows that utilize a 1,000 bp exogenous sequence without known homology to any nucleotide sequence found in humans, mice, or any known human pathogen. These controls are:

• Accurately quantified—digital PCR analysis ensures accurate standard curve generation
• Highly stable
  • DNA spike-in control—double-stranded DNA naturally retains excellent stability
  • RNA spike-in control—RNA sequence is encapsulated in a non-contagious virus-like particle, ensuring it is resistant to temperature changes and RNase digestion
• Easy to integrate—assays are available in the FAM, HEX and CY5 channels to easily integrate into your existing and planned workflows

These spike-in controls were featured in our research posters presented at the 2024 Association for Molecular Pathology (AMP) Annual Meeting & Expo:    

Comprehensive UTI assay panel utilizing exogenous DNA spike-in control
Learn more and download the poster here.

Exogenous RNA virus-like particle (VLPs) for precise molecular diagnostics
Download the poster here.  

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