STEM101 antibody citation list

STEM101 antibody (formerly named SC101) is a mouse monoclonal antibody specific to the human nuclear protein Ku80. It does not cross-react with mouse or rat tissue. This human-specific antibody exclusively labels human nuclei and enables the quantification of engraftment, survival, migration, and differentiation of transplanted human stem cells in xenograft models. Read below for a citation list of studies in which STEM101 was used in peer-reviewed basic, translational, preclinical, and biomedical research.

Acharya, M. M., Christie, L.-A., Hazel, T. G., Johe, K. K. & Limoli, C. L. Transplantation of human fetal-derived neural stem cells improves cognitive function following cranial irradiation. Cell Transplant. 23, 1255–66 (2014).

Acharya, M. M. et al. Defining the optimal window for cranial transplantation of human induced pluripotent stem cell-derived cells to ameliorate radiation-induced cognitive impairment. Stem Cells Transl. Med. 4, 74–83 (2015).

Bible, E. et al. Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by (19)F- and diffusion-MRI. Biomaterials 33, 2858–71 (2012).

Cummings, B. J. et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. Proc. Natl. Acad. Sci. 102, 14069–14074 (2005).

Cummings, B. J., Uchida, N., Tamaki, S. J. & Anderson, A. J. Human neural stem cell differentiation following transplantation into spinal cord injured mice: association with recovery of locomotor function. Neurol. Res. 28, 474–81 (2006).

Guzman, R. et al. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc. Natl. Acad. Sci. U. S. A. 104, 10211–6 (2007).

Haus, D. L. et al. CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice. Stem Cell Res. 13, 214–26 (2014).

Mattis, V. B. et al. Neonatal immune-tolerance in mice does not prevent xenograft rejection. Exp. Neurol. 254, 90–8 (2014).

Salazar, D. L., Uchida, N., Hamers, F. P. T., Cummings, B. J. & Anderson, A. J. Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model. PLoS One 5, e12272 (2010).

Sareen, D. et al. Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord. J. Comp. Neurol. 522, 2707–28 (2014).

Sharmin, S. et al. Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. J. Am. Soc. Nephrol. (2015). doi:10.1681/ASN.2015010096

Smith, E. J. et al. Implantation site and lesion topology determine efficacy of a human neural stem cell line in a rat model of chronic stroke. Stem Cells 30, 785–96 (2012).

Tamaki, S. J. et al. Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis. Cell Stem Cell 5, 310–9 (2009).

Tatarishvili, J. et al. Human induced pluripotent stem cells improve recovery in stroke-injured aged rats. Restor. Neurol. Neurosci. 32, 547–58 (2014).

Tornero, D. et al. Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery. Brain 136, 3561–77 (2013).

Uchida, N. et al. Human neural stem cells induce functional myelination in mice with severe dysmyelination. Sci. Transl. Med. 4, 155ra136 (2012).