Investigating human health and disease at single-cell resolution
View our collection of talks from a panel of worldwide single-cell genomics experts. These were presented during the Takara Bio Focus Day Workshop, hosted with Oxford Global as part of the 2020 NextGen Omics Series UK.
Advances in single-cell combinatorial indexing
In this talk, Dr. Andrew Adey (Oregon Health & Science University) discusses his lab’s combinatorial indexing approach to single-cell sequencing.
Single-cell atlases of the substantia nigra identify Parkinson's disease risk-associated cell types and new gene targets
In this talk, Dr. Caleb Webber (UK Dementia Research Institute, Cardiff) discusses his lab’s approach to building a high-resolution single-nuclei atlas of the substantia nigra in Parkinson’s disease.
Combined single-cell TCR and transcriptomics using the ICELL8
In this talk, Dr. Wilfred van Ijcken (Erasmus MC, Rotterdam) discusses combined single-cell TCR profiling and transcriptome analysis from clinical samples.
Dissection of gene expression heterogeneity at single-cell resolution in CRISPR-Cas9-induced mouse models of acute erythroid leukemia
In this talk, Dr. Ilaria Iacobucci (St. Jude Children’s Research Hospital) discusses the generation of acute erythroid leukemia murine models and their characterization by full-length single-cell RNA-seq.
CD4/CD8 lineage choice at the single-cell level
In this talk, Dr. Matthias Merkenschlager (Imperial College London, UK) discusses approaches to understanding cell fate mechanisms in CD4/CD8 lineage choice.
Somatic CNV detection by single-cell whole-genome sequencing in multiple system atrophy, a sporadic neurodegenerative disorder
In this talk, Dr. Christos Proukakis (UCL Queen Square Institute of Neurology, London, UK) discusses investigation of synucleinopathies, a group of highly variable neurodegenerative disorders.
Single cells in health and disease
In this talk, Dr. Andrew Farmer (Takara Bio USA, Inc.) closes our session with an overview of how single-cell genomics is expanding our understanding of both health and disease.
Panel discussion: Takara Bio Focus Day Workshop
This session features a healthy discussion among all speakers from our event panel. They address the state of single-cell analysis and automation, while answering questions submitted during the event.
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