DNA-seq
Our ThruPLEX and PicoPLEX DNA-Seq library kits enable the generation of high-complexity NGS libraries from a variety of challenging sample types such as cell-free DNA, formalin-fixed paraffin-embedded (FFPE) DNA, and extremely low-input samples.
Our kits and their applications are described in detail in the technical notes and other resources listed below.
Whole genome amplification (WGA)
Single-cell DNA-seq for variant detection
The PicoPLEX Gold Single Cell DNA-Seq Kit is the preferred technology for detecting aneuploidies in embryo biopsies, characterizing the heterogeneity of cancer tissues, profiling circulating immune cells, and more.
Whole genome amplification for variant detection
Single-cell whole genome amplification for CNV and SNV detection.
DNA-seq
Streamlined DNA-seq from challenging samples
Get improved coverage and mutation detection from challenging sample types, regardless of GC content.
DNA-seq from low-volume sample inputs
High-quality NGS libraries from low-input DNA samples.
Whole-exome sequencing
High-quality NGS libraries for whole-exome sequencing from low-input DNA samples.
DNA-seq from FFPE samples
High-quality NGS libraries from FFPE samples.
ThruPLEX FLEX: DNA-seq for cfDNA and FFPE
High-quality NGS libraries from FFPE and cell-free DNA.
ThruPLEX FLEX EF: DNA-seq for cfDNA and FFPE
ThruPLEX DNA-Seq FLEX EF combines the complete, efficient, and accurate workflow of ThruPLEX FLEX with enzymatic fragmentation to produce Illumina-ready libraries.
Comparison note: ThruPLEX FLEX vs NEBNext Ultra II
Learn how ThruPLEX FLEX compares to other end-to-end library prep systems.
Comparison note: ThruPLEX FLEX EF vs KAPA HyperPlus and NEBNext Ultra II FS
Learn how ThruPLEX DNA-Seq FLEX EF compares to other end-to-end library prep systems.
ChIP-seq for epigenetic profiling
High-quality NGS libraries from limited amounts of ChIP DNA.
DNA-seq with molecular tags for rare variant detection
Incorporating unique molecular identifiers (UMIs), ThruPLEX Tag-Seq FLEX offers added power in correcting for polymerase and sequencing errors—key advantages when detecting low-frequency variants.
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