RNA stabilization in cells and tissues—NucleoProtect RNA
NucleoProtect RNA stabilization solution allows for convenient long-term storage of animal cell and tissue samples for subsequent RNA isolation. NucleoProtect RNA is designed to permeate mammalian cells and tissues up to 5 mm in diameter and protect RNA from degradation prior to sample processing. Samples can be preserved at 4°C for up to one month or at or below −20°C for longer periods. NucleoProtect RNA is compatible with diverse downstream RNA purification methods, including NucleoSpin RNA kits.
NucleoProtect RNA stabilization solution allows for convenient long-term storage of animal cell and tissue samples for subsequent RNA isolation. NucleoProtect RNA is designed to permeate mammalian cells and tissues up to 5 mm in diameter and protect RNA from degradation prior to sample processing. Samples can be preserved at 4°C for up to one month or at or below −20°C for longer periods. NucleoProtect RNA is compatible with diverse downstream RNA purification methods, including NucleoSpin RNA kits, and provides comparable performance to alternative RNA stabilization reagents such as RNAlater solution. Following storage in NucleoProtect RNA, high-quality RNA with RIN values of 9 or 10 can be obtained from mammalian tissues and cells, respectively.
Overview
- Stabilization reagent for preservation of RNA in mammalian cells or tissues prior to sample processing
- Compatible with most downstream RNA purification methods, including NucleoSpin RNA kits
- Allows for recovery of high-quality RNA with RIN values of 9 or 10
- Enables preservation of samples at 4°C for up to one month or at or below −20°C for longer-term storage
More Information
| Technology | RNA stabilization reagent |
| Processing | Add 10 volumes to sample |
| Sample material | Human/animal cells and tissues (max. 5-mm diameter) |
| Storage time |
18–25°C, ≤7 days 4°C, ≤1 month −20°C/−80°C, long term |
| Typical RIN after RNA isolation* | 9–10 for RNA purified from mammalian tissues and cultured cells, respectively |
*Data generated using NucleoSpin kits; RNA integrity strongly depends on quality and handling of samples prior to stabilization.
Applications
- Preservation of RNA in animal cells or tissues for short- to long-term storage prior to RNA purification and downstream sample processing
- RNA purification, cDNA synthesis, qPCR, NGS
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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