Titanium Taq

Cardiology

Jiang, X., et al. Effect of renin-angiotensin-aldosterone system gene polymorphisms on blood pressure response to antihypertensive treatment. Chin. Med. J. 120, 782–786 (2007).

Cancer

Eldai, H. et al. Novel genes associated with colorectal cancer are revealed by high resolution cytogenetic analysis in a patient specific manner. PLoS One 8, e76251 (2013).

Lopes, B. A. et al. COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia. Oncotarget 7, 53064–53073 (2016).

Weyant, G. W. et al. BRAF mutation testing in solid tumors: a methodological comparison. J. Mol. Diagn. 16, 481–485 (2014).

Cell-free DNA

Schwartz, S., Kohan, M., Pasion, R., Papenhausen, P. R. & Platt, L. D. Clinical experience of laboratory follow-up with noninvasive prenatal testing using cell-free DNA and positive microdeletion results in 349 cases. Prenat. Diagn. 38, 210–218 (2018).

Neurobiology

Brouwers, N., et al. Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease. Brain 129, 2984–2991 (2006).

Otology

Hilgert, N., et al. Mutation analysis of TMC1 identifies four new mutations and suggests an additional deafness gene at loci DFNA36 and DFNB7/11. Clin. Genetics 74, 223–232 (2008).

Pathogens

Buelow, D. R., et al. Comparison of two multiplexed PCR assays for the detection of HSV-1, HSV-2, and VZV with extracted and unextracted cutaneous and mucosal specimens. J. Clin. Virol. 58, 84–88 (2013).

Stellrecht, K. A., et al. Comparison of three real-time PCR methods for the quantification of polyomavirus BK. J. Clin. Virol. 56, 354–359 (2013).

Oncology

Gardina, P., et al. Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays. BMC Genomics 9, 489 (2008).

Immunology

Svarovskaia, E., et al. Low-level K6SR mutation in HIV-1 reverse transcriptase of treatment-experienced patients exposed to abacavir or didanosine. J. Acquir. Immune Defic. Syndr. 46, 174–180 (2008).

Pathogens

Balamurugan, R., et al. PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis. J. Clin. Microbiol. 44, 1884–1886 (2006).

Techniques development

Barker, D., et al. Two methods of Whole-Genome Amplification enable accurate genotyping across a 2320-SNP linkage panel. Genome Res. 14, 901–907 (2004).

Karlsson, H., et al. Extraction of RNA from dried blood on filter papers after long-term storage. Clinical Chem. 49, 979–981 (2003).

Noda, N., et al. Estimation of single-nucleotide polymorphism allele frequency by alternately binding probe competitive polymerase chain reaction. Analytica Chemica Acta 608, 211–216 (2008).

Oncology

Karasawa, K. & Arakawa, H. Detection of telomerase activity using microchip electrophoresis. J. Chromatogr. B 993-994, 14–19 (2015).

Cardiology

Haver V.G. et.al. Leukocyte telomere length and left ventricular function after acute ST-elevation myocardial infarction: data from the glycometabolic intervention as adjunct to primary coronary intervention in ST elevation myocardial infarction (GIPS-III) trial. Clin Res Cardiol. 104, 812–21 (2015).

Neuner, B. et al. Telomere length is not related to established cardiovascular risk factors but does correlate with red and white blood cell counts in a German blood donor population. PLoS One 10, (2015).