Optimizing materials and methods for cancer research
Good science begins with selecting the right methods and reagents, especially when research targets are challenging. In this work, cancer researchers developed a method to amplify challenging BRCA targets, including those that are GC-rich or over 13 kb in length, using two-step PCR under a single set of conditions.
Read about how the researchers developed their long-range PCR protocol for BRCA1 and BRCA2