Albumin detection
Albumin is an approximately 66-kDa protein that is present in blood at very high concentrations. In addition to maintaining blood's osmotic pressure, albumin is also known to play a role in transporting fatty acids and a variety of other substances upon binding with them. Serum albumin levels also serve as an indicator of liver health and function since these proteins are hepatically synthesized. Furthermore, because albumin is renally excreted, albumin level in the kidney is a potential early diagnostic marker for diabetic nephropathy. In fact, studies have found that albumin levels in the urine are slightly increased (i.e., microalbuminuria) prior to the generalized protein increase (i.e., proteinuria) that can occur in patients with diabetes.
Albumin is an approximately 66-kDa protein that is present in blood at very high concentrations. In addition to maintaining blood's osmotic pressure, albumin is also known to play a role in transporting fatty acids and a variety of other substances upon binding with them. Serum albumin levels also serve as an indicator of liver health and function since these proteins are hepatically synthesized. Furthermore, because albumin is renally excreted, albumin level in the kidney is a potential early diagnostic marker for diabetic nephropathy. In fact, studies have found that albumin levels in the urine are slightly increased (i.e., microalbuminuria) prior to the generalized protein increase (i.e., proteinuria) that can occur in patients with diabetes.
ELISAs for albumin detection
The Human Albumin EIA Kit is a colorimetric sandwich ELISA designed to quantitatively measure human albumin levels. The human albumin ELISA kit can be used to quickly and easily measure albumin levels in human serum and other bodily fluids.
The Mouse Albumin EIA Kit is a sandwich-type mouse albumin assay kit that uses two rat monoclonal antibodies generated against mouse albumin. The kit makes it possible to easily measure mouse albumin in vitro and in vivo. Since the assay is performed using monoclonal antibodies, it provides excellent specificity because these antibodies do not cross-react with albumin from other species.
Overview
Albumin | MK132 | ELISA | Human | Cross‑reactivity with bovine, horse (male), porcine, rat and mouse serum samples (only at low serum dilution ratios) Albumin was detected in highly diluted human serum samples (2 x 105) |
Albumin | MK133 | ELISA | Mouse | Does not cross-react with other species |
More Information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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