von Willebrand factor (VWF) detection
The von Willebrand Factor (VWF) Antibody (Clone VW92-3) recognizes von Willebrand factor protein, a blood glycoprotein. The exact epitope of the anti-von Willebrand factor monoclonal antibody is yet to be determined. Clone VW92-3 is intended for general research use.
Lyophilized. Dissolve in 100 µl of distilled water (final concentration: 2.0 mg/ml with 0.1% sodium azide)
Fujimura, Y. et al. von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib. J. Biol. Chem. 261, 381–5 (1986).
Fujimura, Y. et al. The interaction of botrocetin with normal or variant von Willebrand factor (types IIA and IIB) and its inhibition by monoclonal antibodies that block receptor binding. Thromb. Haemost. 68, 464–9 (1992).
Girma, J. P., Chopek, M. W., Titani, K. & Davie, E. W. Limited proteolysis of human von Willebrand factor by Staphylococcus aureus V-8 protease: isolation and partial characterization of a platelet-binding domain. Biochemistry 25, 3156–63 (1986).
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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