Immune profiling involves the analysis of T- and B-cell receptors (TCRs/BCRs). We offer a variety of human TCR and BCR profiling kits to help researchers investigate immune cell development, examine mechanisms of autoimmune diseases and cancers, and develop models for immunotherapy of specific diseases. Our kits streamline sample preparation by combining our SMART (Switching Mechanism at 5' End of RNA Template) technology with 5' RACE to capture V(D)J sequences starting from RNA samples.
Our kits identify expressed receptor sequences and provide greater sensitivity for more comprehensive identification of unique functional variants. These kits also give reproducible, sensitive, and unbiased results from a wide range of input amounts. Some of our kits also contain unique molecular indexes (UMIs) to correct for PCR errors, providing further confidence in the sensitivity and reproducibility of your data.
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