Epigenetics and smRNA-seq

Learn how to take the SMARTer approach for your epigenetic and small RNA sequencing analyses.

Epigenetics is emerging as a key tool for understanding the mechanistic underpinnings that regulate gene expression. Monitoring methylation, DNA accessibility, DNA-protein interactions, and non-coding small RNA functions can help to further understand the molecular landscape of cellular function, particularly when coupled with RNA-seq and DNA-seq. Methods of interrogating these epigenetic factors are described in the technical notes below.

Full-length small RNA libraries

Accurate miRNA representation in microRNA-seq

ChIP-seq libraries from ssDNA

Methylated DNA-seq

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