Gene function webinars
View key videos on applications for gene editing, viral delivery, and inducible gene expression
CRISPR/Cas9 comprises a set of powerful gene editing tools that are revolutionizing the field of biology, with the promise to create new research models for disease and to, in the future, perhaps prevent or cure disease. These tools are providing unprecedented efficiency and precision for knockout and knockin workflows. We offer a complete line of products for CRISPR/Cas9-based gene editing experiments, as well as viral and gesicle delivery systems for Cre recombinase-based genome editing.
The curated list of webinars below offers insight, guidance, and support on these topics from guest speakers and our own R&D scientists.
Guest webinar: choosing the right HDR template for knockin experiments
In this webinar, Theo Roth (UCSF) talks about the delivery of DNA through electroporation of ex vivo primary human T cells, and discusses different types of homology-directed repair (HDR) templates and their various applications. Special attention is devoted to varying effects on editing efficiency, cell viability, ease of production, and therapeutic applicability.
Lentiviral CRISPR/Cas9 knockout screening made simple
In this webinar, Thomas Quinn, M.S. (Takara Bio USA, Inc.) discusses the design and execution of genome-wide CRISPR/Cas9-based knockout screens using pooled sgRNA libraries. He also describes features and benefits of the Guide-it CRISPR Genome-Wide sgRNA Library System and NGS analysis kit, a complete solution developed with the aim of making lentiviral CRISPR/Cas9 screening accessible to all.
A fast and reliable method for SNP screening in genome editing experiments
In this webinar, Montse Morell, Ph.D. (Takara Bio USA, Inc.) presents the Guide-it SNP Screening Kit, a solution she developed to enable rapid, accurate detection of single-nucleotide substitutions and confirmation of successful HDR in edited cells. She also demonstrates an application of the kit in the development of disease models using iPSCs.
Simplified genome modification
Watch this video to learn more about our Cre Recombinase Gesicles.
Studying the function of genes by controlling their expression
In this webinar Dr. h.c. Hermann Bujard, University of Heidelberg, Germany, gives an introduction to the underlying principles of the Tet technology and the concept of gene regulation by tetracyclines. Professor Bujard also discusses the development of the Tet Systems components over time and their advantages as well as giving a review of results obtained by using the technology in transgenic mice. Learn about the underlying principles of the Tet System in the inventor's own words, Tet-On versus Tet-Off, and optimization of the technology.
Controlling gene expression in transgenic mice
In this webinar Dr. Kai Schönig, Central Institute of Mental Health, Mannheim, Germany, focuses on the use of Tet technology in transgenic mice. Options on how to set up the Tet inducible system in mice will be discussed. Dr. Schönig will also present a number of in vivo applications which demonstrate the potential of this powerful technology. Learn how to establish the Tet System in transgenic mice in vivo applications and on-going developments for in vivo use of tetracycline-inducible expression.
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