Early-access program: spike-in controls
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An exogenous control is crucial to improving molecular assay workflows as it eliminates false negatives and false positives, ensures accurate detection, validates extraction and amplification, enables quantification and normalization, and promotes standardization. We have developed unique spike-in controls for both DNA- and RNA-based qPCR workflows that utilize a 1 kb exogenous sequence without known homology to any nucleotide sequence found in humans, mice, or any known human pathogen. These controls are:
- Accurately quantified—digital PCR analysis ensures accurate standard curves can be generated
- Highly stable
- DNA spike-in control— double stranded DNA naturally retains excellent stability
- RNA spike-in control—RNA sequence is encapsulated in a non-contagious virus like particle, ensuring it is resistant to temperature changes and digestion by RNase
- Easy to integrate—assays are available in the FAM, HEX and CY5 channels to easily integrate into your existing and planned workflows
These spike-in controls were featured in our research posters presented at the Association for Molecular Pathology (AMP) Annual Meeting & Expo:
Comprehensive UTI assay panel utilizing exogenous DNA spike-in control
Learn more and download the poster here.
Exogenous RNA virus-like particle (VLPs) for precise molecular diagnostics
Download the poster here.
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