iDimerize™ Inducible Homodimer System

How does iDimerize technology work? A chemical inducer of dimerization, or “dimerizer”, is a cell-permeant organic small molecule with two separate motifs that each bind with high affinity to a specific protein module (Dmr domain) fused onto the protein(s) of interest
Activation of a signal transduction pathway through dimerization of a cell surface receptor protein
Signal transduction example 2
Signal transduction example 1: Inducing a Programmed Cell Death Pathway (Inducible Apoptosis)
Exploiting fas-mediated apoptosis to induce programmed cell death