Lenti-X™ Tet-One™ Inducible Expression System (Puro)
Seven out of eight Tet-One clones show more than 1,000-fold induction of expression
The Tet-One system is highly sensitive to low levels of doxycycline (Dox)
Lenti-X Tet-One Vector maps
Tet-One System Mechanism — The Tet-On 3G transactivator protein is expressed constitutively from the human PGK promoter (PPGK) but is unable to bind to the TRE3G promoter (PTRE3G) in the absence of doxycycline (Dox)