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Cellartis cardiomyocytes derived from human induced pluripotent stem cells

Cellartis cardiomyocytes are a highly homogeneous population of cardiomyocytes derived from human induced pluripotent stem (iPS) cells (ChiPSC22). The iPS cells have been differentiated into spontaneously beating cardiomyocytes in vitro. These cells have been dissociated into a single-cell suspension and frozen in vials. The Cellartis Cardiomyocytes (from ChiPSC22) Kit contains one vial of cardiomyocytes (>3 x 10⁶ viable cells), one bottle of Cellartis CM Thawing Base, and one bottle of Cellartis CM Culture Base.

Cat. #

Product

Size

Price

License

Quantity

Details

Y10075

Cellartis® Cardiomyocytes (from ChiPSC22) Kit

1 Kit

$812.00

License Statement

ID Number

C005

This product is manufactured and sold by Takara Bio Europe AB based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.

L67

This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein.

This Product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) based on a patent license from iPS Academia Japan, Inc. No express or implied license is granted to the purchaser.

"Product" means the differentiated cells manufactured and sold by Takara Bio Inc.

"Internal research purpose" means the use of this Product as a tool of internal research for the sole benefit of the purchaser or purchaser’s contract research customer, (including screening of compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use), provided, however, that the following activities using this Product are strictly prohibited and expressly excluded from Internal research purposes:
1) Administration of this Product to humans.
2) Use of this Product for the diagnostic testing, prevention, or treatment of human and/or animal diseases.
3) Use of this Product in studies involving administration to humans for cell therapy, regenerative medicine etc.

Purchaser may use this Product for its own Internal research purposes.

Purchaser shall not use the Products for its commercial purposes.

Notwithstanding the foregoing, the purchaser of this Product may provide third parties with contract research services by using this Product only for such third party’s Internal research purposes.

Cellartis Cardiomyocytes (from ChiPSC22) are human cardiomyocytes derived from a human induced pluripotent stem (iPS) cell line. The cells are provided frozen with thawing and maintenance media bases.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Components

Y10063

Cellartis® CM Culture Base

90 mL

$83.00

Cellartis CM Culture Base is a maintenance medium used to culture Cellartis Cardiomyocytes.

Notice to purchaser

Components

Y10062

Cellartis® CM Thawing Base

32 mL

$37.00

Cellartis CM Thawing Base is a medium used for thawing Cellartis Cardiomyocytes.

Notice to purchaser

Components

Overview

Electrophysiological profile highly resembling adult human primary cardiomyocytes
Respond as expected to cardiac stimuli
Derived with a robust, efficient cardiac differentiation protocol, without genetic engineering or selection
Cells are provided with basal medium for thawing and culture

More Information

Applications

Safety pharmacology
Cardiotoxicity testing
Discovery of novel cardiac drug targets
Phenotypic screening
High-content analysis (HCA)

Components

1 vial Cellartis cardiomyocytes (>3 x 10⁶ viable cells)
1 bottle Cellartis CM Thawing Base (32 ml)
1 bottle Cellartis CM Culture Base (90 ml)

Additional product information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.

Takara Bio USA, Inc.
United States/Canada: +1.800.662.2566 • Asia Pacific: +1.650.919.7300 • Europe: +33.(0)1.3904.6880 • Japan: +81.(0)77.565.6999
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. © 2018 Takara Bio Inc. All Rights Reserved. All trademarks are the property of Takara Bio Inc. or its affiliate(s) in the U.S. and/or other countries or their respective owners. Certain trademarks may not be registered in all jurisdictions. Additional product, intellectual property, and restricted use information is available at takarabio.com.

Cellartis cardiomyocytes derived from human induced pluripotent stem cells

Notice to purchaser

Cellartis Cardiomyocytes (from ChiPSC22) respond in a dose-dependent manner to hERG blocker E4031 as measured by MEA (MED64 AlphaMED MEA system)

Cellartis Cardiomyocytes (from ChiPSC22) express cardiomyocyte markers, including cTroponin (red)

Notice to purchaser

Notice to purchaser

Overview

More Information

Applications

Components

Additional product information