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  • ‹ Back to Apoptosis detection kits
  • Annexin V apoptosis assay
  • PARP antibody
  • ApoAlert caspase assays
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Home › Products › Gene function › Cell biology assays › Apoptosis detection kits › PARP antibody

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PARP monoclonal antibody

Poly(ADP-ribose) polymerase (PARP) is a substrate for CPP32/caspase-3, a member of the ICE family of proteases. The PARP monoclonal antibody can be used to detect PARP cleavage by western blot analysis, providing a useful marker for early apoptosis.

Cat. # Product Size License Quantity Details
630210 PARP Monoclonal Antibody (Mouse IgG1, C-2-10) 50 uL USD $630.00

Clone C-2-10 recognizes 116-kDa native poly (ADP-ribose) polymerase (PARP) and the 85-kDa apoptosis-related cleavage product. This mouse monoclonal antibody cross-reacts with human, monkey, hamster, rat, and mouse. PARP is a target of proteolytic cleavage by the ICE-family proteases CPP32 and Mch2α during the early stages of apoptosis. PARP cleavage is an early indicator of apoptosis. Native PARP has a molecular weight of 116 kDa; cleavage yields fragments of 85 kDa and 25 kDA.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Documents Components

Overview

  • PARP monoclonal antibody recognizes native and cleaved poly(ADP-ribose) polymerase or PARP (PARP cleavage is an early indicator of apoptosis)

More Information

Applications

  • Use the PARP antibody to detect the early stages of apoptosis via western blotting, immunocytochemistry, or ELISA

Additional product information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.

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  • Try BcaBEST DNA Polymerase ver.2.0
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