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mLST8 (L17) polyclonal antibody
Human mTOR-associated protein, LST8 homolog (mLST8) is a subunit of two protein complexes that associate with mammalian target of rapamycin (mTOR), known as mTORC1 and mTORC2. Both complexes regulate cell growth and survival in response to nutrient and hormonal signals. Within mTORC1, mLST8 interacts directly with and enhances the kinase activity of mTOR. In nutrient-poor conditions, mLST8 stabilizes the interaction between mTOR and regulatory-associated protein of mTOR (RAPTOR). The MLST8 gene is conserved over a wide range of species, from yeast to human. mLST8 is also known as Gable (GBL), GbetaL, mammalian lethal with SEC13 protein 8, TORC subunit LST8, target of rapamycin complex subunit LST8, G protein beta subunit-like, POP3, and WAT1.
This product is an affinity-purified IgG antibody that recognizes human mLST8 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human mLST8 protein.
- Cat.#: 28013A, 28013B
- Target Name: Human mLST8 protein
- Antigen: Human mLST8 N-terminal synthetic peptide
- Application: WB, IP
- Target Entrez Gene ID: 64223
Recommended antibody concentration (the optimal concentration should be determined empirically):
- Western blot: 0.5–5.0 µg/ml
- Immunoprecipitation: 1–5 µg/ml
Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.
Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).
Gable, GBL, GbetaL, mammalian lethal with SEC13 protein 8, TORC subunit LST8, target of rapamycin complex subunit LST8, G protein beta subunit-like, POP3, WAT1
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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