- Alzheimer's disease
- Bone research
- Brain and CNS
- Cancer and inflammation
- Cell adhesion and ECM
- Environmental hazards
- Epigenetic antibodies
- Metabolic diseases
- mTOR signaling
- Signal transduction
- Stem cell research antibodies
- Virus research
- Miscellaneous research areas
Human CAD antibody
This product is an affinity-purified IgG antibody that recognizes human CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot detection or immunoprecipitation of human CAD protein. The antibody is a useful tool for research on mTOR signaling and/or the regulation of nucleic acid biosynthesis.
mTOR is a serine/threonine protein kinase that controls cell growth, proliferation, and survival. CAD was identified as a binding partner with mLST8, a component of the mTOR complex. CAD is involved in de novo pyrimidine synthesis and is regulated by phosphorylation; it is thought that CAD is regulated by the mTOR pathway through association with mLST8.
- Cat. # 28141A/B
- Target Name: Human CAD
- Antigen: Human CAD C-terminal synthetic peptide
- Application: WB, IP
- Target Entrez Gene ID: 64223
Recommended antibody concentration (the optimal concentration should be determined empirically):
- Western blot: 1.0 µg/ml
- Immunoprecipitation: 3.0 µg/ml
Lyophilized; contains 1% BSA and 0.05% NaN3
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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