Anti-SEP1 rabbit IgG antibody
Strand exchange protein 1 (SEP1) homolog was reported as a human gene responsive to stimulation by glial cell-derived neurotrophic factor (GDNF) in neuroblastoma cells. It was subsequently characterized as the human homolog to yeast XRN1 protein, a 5'-3' exoribonuclease. SEP1 is involved in mRNA degradation, and in a variety of other nuclear and cytoplasmic functions. It may also act as a tumor suppressor protein in osteogenic sarcoma (OGS). SEP1 is also known as XRN1 and 5'-3' exoribonuclease 1.
This product is an affinity-purified IgG antibody that recognizes human and mouse SEP1/XRN1 protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human and mouse SEP1/XRN1 protein.
- Cat.#: 28043A, 28043B
- Target Name: Human SEP1/XRN1 protein
- Antigen: Human SEP1/XRN1 synthetic peptide
- Specificity: Reacts with human and mouse SEP1
- Application: WB, IHC, IP
- Target Entrez Gene ID: 54464
Recommended antibody concentration (the optimal concentration should be determined empirically):
- Western blot: 0.1 µg/ml
- Immunohistochemical techniques: 1 µg/ml
- Immunoprecipitation: 1 µg/ml
Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.
Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 ml H2O (final concentration 100 µg/ml).
XRN1, 5'-3' exoribonuclease 1
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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