Anti-human RON (G1385) rabbit IgG antibody
Macrophage stimulating 1 receptor (c-met-related tyrosine kinase), encoded by the MST1R gene, is a cell-surface receptor that binds macrophage-stimulating protein (MSP). It was previously known as RON. The precursor protein is cleaved to generate the mature form, a heterodimer of disulfide-linked alpha and beta subunits. The beta subunit of MST1R/RON is phosphorylated at tyrosine residues upon activation by MSP. MST1R/RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation, and survival at the wound site. MST1R/RON is also known as CDw136, protein-tyrosine kinase 8 (PTK8), c-met-related tyrosine kinase, macrophage-stimulating protein receptor, MSP receptor, p185-Ron, CD136, MST1R variant RON30, MST1R variant RON62, and RON variant E2E3.
This product is an affinity-purified IgG antibody that recognizes human MST1R/RON protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human MST1R/RON protein.
Cat.#: 18531A, 18531B
- Target Name: Human MST1R/RON protein
- Antigen: Human MST1R/RON C-terminal synthetic peptide
- Application: WB, IP
- Target Entrez Gene ID: 4486
Recommended antibody concentration (the optimal concentration should be determined empirically):
- Western blot: 2–10 µg/ml
- Immunoprecipitation: 2–10 µg/ml
Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.
Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 ml H2O (final concentration 100 µg/ml).
Macrophage stimulating 1 receptor (c-met-related tyrosine kinase); MST1R, RON, CDw136, protein-tyrosine kinase 8, PTK8, c-met-related tyrosine kinase, macrophage-stimulating protein receptor, MSP receptor, p185-Ron, CD136, MST1R variant RON30, MST1R variant RON62, RON variant E2E3
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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