Gastrin receptor (OK-524) polyclonal antibody
Gastrin is a peptide hormone that stimulates secretion of gastric acid by the parietal cells of the stomach. Gastrin binds to a G-protein coupled receptor encoded by the CCKBR gene that also binds cholecystokinin (CCK), a brain regulatory peptide. The receptor is therefore known as the gastrin/cholecystokinin type B receptor. It is also known as cholecystokinin B receptor, cholecystokinin-2 receptor, CCK-B, CCKB-R, CCKRB, CCK2R, and GASR. The gastrin/cholecystokinin receptor is expressed mostly in central nervous system and the gastrointestinal tract. A misspliced transcript variant of the CCKBR gene that includes an intron has been associated with colorectal and pancreatic tumors.
This product is an affinity-purified IgG antibody that recognizes human gastrin receptor protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human gastrin receptor protein.
- Cat.#: 28103A, 28103B
- Target Name: Human gastrin receptor
- Antigen: Human gastrin receptor C-terminal synthetic peptide
- Application: WB, IHC
- Target Entrez Gene ID: 887
Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.
Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 ml H2O (final concentration 100 µg/ml).
Cholecystokinin B receptor, cholecystokinin-2 receptor, CCK-B, CCKB-R, CCKRB, CCK2R, GASR
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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