- Alzheimer's disease
- Bone research
- Brain and CNS
- Cancer and inflammation
- Cell adhesion and ECM
- Environmental hazards
- Epigenetic antibodies
- Metabolic diseases
- mTOR signaling
- Signal transduction
- Stem cell research antibodies
- Virus research
- Miscellaneous research areas
Dipeptidyl peptidase-4 detection—DPP4 ELISA
This kit is a solid-phase sandwich ELISA that uses two antibodies that are highly specific to human dipeptidyl peptidase-4 (DPP4): one is precoated on the ELISA plate, and the other is HRP-conjugated. This assay kit can be used to measure human DPP4 protein in serum, EDTA plasma, urine, cerebrospinal fluid, and cell culture supernatants.
DPP4 (also known as CD26) is a transmembrane glycoprotein receptor that is involved in T-cell activation. In addition, DPP4 functions as a serine exopeptidase to regulate various physiological processes by cleavage of substrates including hormones, growth factors, chemokines, and incretins. One DPP4 target is glucagonlike peptide-1 (GLP-1), an incretin that regulates insulin secretion; recently, DPP4 inhibitors have been developed for the treatment of diabetes. In addition to regulating glucose metabolism, it is thought that DPP4 plays a role in tumor biology, and its expression is used as a marker for various cancers.
- Capable of measuring human DPP4 protein
- Sensitivity: 8.58 pg/ml
- This kit can be used for measuring human DPP4 protein in serum, EDTA plasma, urine, cerebrospinal fluid, and cell culture supernatants.
Range of assay: 125–8,000 pg/ml
Assay sensitivity: 8.58 pg/ml
Assay duration: Approximately 2.0 hours
Test specimen type: Serum, EDTA plasma, urine, cerebrospinal fluid, cell culture supernatants
Specificity: Shows ≤0.1% cross-reactivity with mouse and rat DPP4
Sample volume per well: 100 µl
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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