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- Bcl-1 cyclin D1
- COX-1 COX-2
- Fatty acid synthase
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Surfactant protein A1 (SP-A or SP-A1) is a member of the C-type lectin family of proteins, known as collectins. In humans, it is encoded by the SFTPA1 gene. SP-A is the major protein component of pulmonary surfactant, a lipoprotein complex secreted by the alveolar type II cell. Pulmonary surfactant reduces surface tension in the alveolus and prevents alveolar collapse during exhalation. In addition to its role as a surfactant, SP-A modulates the alveolar immune response to microbes and inhaled particulate matter. SP-A is also expressed in nonalveolar cells, and is thought to be involved in functions such as immune cell proliferation, stimulation of proinflammatory cytokine expression, and control of reactive oxygen species. Mutations in the SFTPA1 gene are associated with idiopathic pulmonary fibrosis.
This product is an affinity-purified IgG antibody that recognizes human SP-A protein. The antibody was raised in mouse using purified SP-A protein and can be used for immunohistochemical (IHC) detection of human SP-A protein.
- Target Name: Human SP-A protein
- Antigen: Human SP-A purified protein
- Target Entrez Gene ID: 653509
Recommended antibody concentration (the optimal concentration should be determined empirically):
- Immunohistochemical techniques: 5 µg/ml
Lyophilized: stable for 5 years at 2–8°C. In solution: stable for 2 years at –20°C.
Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 ml H2O (final concentration 100 µg/ml).
Alveolar proteinosis protein, 35 kDa pulmonary surfactant-associated protein, pulmonary surfactant-associated protein A1, surfactant protein A1B, collectin-4, SP-A1, PSAP, PSPA, SFTP1, SFTPA, SPA, SPA1, COLEC4, and SFTPA1B.
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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