- Alzheimer's disease
- Bone research
- Brain and CNS
- Cancer and inflammation
- Cell adhesion and ECM
- Environmental hazards
- Epigenetic antibodies
- Metabolic diseases
- mTOR signaling
- Signal transduction
- Stem cell research antibodies
- Virus research
- Miscellaneous research areas
Glial fibrillary acidic protein (GFAP) detection
Glial fibrillary acidic protein (GFAP), a 50 kDa protein, is a major intermediate filament protein in mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in the GFAP gene in humans cause Alexander disease, a very rare, fatal neurodegenerative disease that mostly affects infants and children and results in developmental delay and changes in physical characteristics. GFAP is also known as FLJ45472.
This product is an affinity-purified IgG antibody that recognizes GFAP protein. The antibody was raised in mouse using bovine GFAP, and can be used for immunohistochemical (IHC) detection of GFAP protein.
- Target name: Bovine GFAP protein
- Antigen: Bovine GFAP protein
- Application: IHC
- Specificity: Reacts with human, rat, and bovine GFAP
- Target Entrez Gene ID: 281189
Recommended antibody concentration (the optimal concentration should be determined empirically):
- Immunohistochemical techniques: 200X dilution
Lyophilized: stable for 5 years at 2–8°C. In solution: stable for 2 years at –20°C.
Lyophilized from an antibody solution containing 0.05% NaN3. To use, reconstitute in 1.0 ml H2O.
Additional product information
Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.
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