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TCR-seq methods: when to use which
Examining a patient's immune response is crucial to improve our understanding of immune-related diseases and to develop new immunotherapies. T-cell receptor (TCR) diversity analysis using NGS has proven instrumental in probing for these questions—but no systematic study comparing TCR-seq methods was available until recently.
In this on-demand webinar, Dr. Encarnita Mariotti-Ferrandiz presents the results of her extensive benchmarking of current TCR-seq methods, recently published in Nature Biotechnology.
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- Understand key characteristics and selection criteria for immune-profiling techniques like RACE and multiplex PCR
- Systematically compare the advantages and drawbacks of nine commercial and academic TCR-seq methods
- Discuss exciting next steps for the T-cell receptor field
About the presenter
Encarnita Mariotti-Ferrandiz, PhD
Encarnita Mariotti-Ferrandiz is an Associate Professor of Immunology from Sorbonne Université at the Pitié-Salpêtrière Hospital in Paris. Since her PhD, she has been involved in deciphering the Adaptive Immune Receptor Repertoire (AIRR) diversity in health and pathology with a major focus on T-cell biology. With this expertise, she co-chairs the Biological Resources working group of the AIRR-Community to assess the needs and development of AIRR-sequencing controls and standards.
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