What our customers are saying:
…we employ the SMART‑Seq mRNA Long Read Kit, primarily for the characterization of intronic variants in the diagnostic evaluation of hereditary tumor predisposition syndromes. Additionally, this approach is utilized in the investigation of patients with (ultra) rare genetic disorders. In our experience, the SMART‑Seq mRNA Long Read Kit offers substantially enhanced vertical coverage of low-abundance transcripts and superior performance in the structural resolution of long and complex mRNA isoforms, compared to alternative methods currently available on the market.
Dr. Matthias Linke
Laboratory Head of Preimplantation Genetic Diagnosis
Institute of Human Genetics
Johannes Gutenberg-Universität Mainz
Frankfurt Rhine-Main Metropolitan Area
Sample type: tumor tissue
Biological insights unlocked by:
- Reliable capture of intronic variants in an ultra-rare genetic disease
- Confident resolution of complex RNA isoforms for evaluation of tumors
…we're developing RNA based liquid biopsies and…we're really excited about discovering biomarkers, not just for cancer early detection, but also for precancer early detection…these pre-malignant states that predispose people to cancer, we are able to identify RNA signals or biomarkers that tell us whether someone has this precancerous condition and is likely to progress to cancer…When I think of Takara Bio, I think of great reagents for molecular biology, for transcriptomics. And we use them all the time in our lab and they've been really helpful for us...they really enable us to do a lot of the experiments that we're doing.
Dr. Daniel Kim
Assistant Professor
University of California, Santa Cruz
Sample type: liquid biopsies
Biological insights unlocked by:
- Identifying biomarkers for early cancer detection
- Discovering biomarkers for pre-malignant states
Discover insights beyond the reach of fragmented short-read methods!
Full length transcripts for deeper understanding
- Detect rare or unknown variants, isoform shifts, novel fusion events, transcriptome changes in rare cell populations and therapeutic targets
- Untangle complex biological processes by capturing more—and longer—transcripts
- Reveal biomarkers for precision medicine studies from a variety of samples
Enhanced coverage of transcripts and superior performance in the resolution of long mRNA isoforms compared to other methods
Evaluating the performance of SMART-Seq mRNA Long Read technology for sensitivity and performance compared to competitor's kit.
