Biomarker discovery with the Shasta Single Cell System
The Shasta Single Cell System opens new avenues for biomarker discovery. Paired with innovative assay technologies and easy-to-use bioinformatics software, it enables exploration of the whole genome or transcriptome in single-cells at unprecedented throughput.
This technology has been featured at numerous professional conferences such as Advances in Genome Biology and Technology (AGBT), Association of Biomolecular Resource Facilities (ABRF), American Society of Human Genetics (ASHG), Festival of Genomics, and Single Cell Genomics.
View the latest data presented at the Society for Laboratory Automation and Screening (SLAS) conference 2026 here.
Automated single-cell and bulk NGS library preparation at the nanoliter scale maintains sensitivity while reducing reagent use
Automated, nanoliter-scale NGS library preparation using the Shasta® Single Cell System maintains sensitivity while dramatically reducing reagent use. By combining automated nanoliter dispensing with our flagship NGS technologies, you can cut reagent consumption by up to 300-fold versus plate-based library prep kits, while maintaining sensitivity.
From whole-genome amplification (WGA) to RNA-seq, prepare high-quality libraries and reduce reagent use.
The Shasta Single Cell System:
- Uses positive-displacement nanosyringes to mix and dispense 25–100 nl volumes
- Dispenses samples, reagents, and barcodes into a 5,184-nanowell chip in 30 min
For WGA library prep, the system:
- Reduces reagent use by ~100-fold
- Detects expected copy number variation (CNV) aneuploidies in >90% of cells
For bulk mRNA library prep, the system:
- Reduces reagent use by up to 300-fold
- Detects ~7,000 genes on average, with comparable sensitivity
Learn more
Shasta resources
Elevate your knowledge by exploring applications and data from the Shasta Single Cell System.
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